19 F-substituted amino acids as an alternative to fluorophore labels: monitoring of degradation and cellular uptake of analogues of penetratin by 19 F NMR
19 F-substituted amino acids as an alternative to fluorophore labels: monitoring of degradation and cellular uptake of analogues of penetratin by 19 F NMR
Abstract
Current methods for assessment of cellular uptake of cell-penetrating peptides (CPPs) often rely on detection of fluorophore-labeled CPPs. However, introduction of the fluorescent probe often confers changed physicochemical properties, so that the fluorophore-CPP conjugate may exhibit cytotoxic effects and membrane damage not exerted by the native CPP. In the present study, introduction of...
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Atomic-level changes in ALS-linked protein - Science Daily
Atomic-level changes in ALS-linked protein - Science Daily
Atomic-level changes in ALS-linked protein Science DailyA new study details the minute changes -- down to the level of individual atoms -- that cause a particular protein to form cell-damaging clumps associated with ...
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01-07-2019 05:49 AM
[NMR paper] Pyruvate cellular uptake and enzymatic conversion probed by dissolution DNP-NMR: the impact of overexpressed membrane transporters.
Pyruvate cellular uptake and enzymatic conversion probed by dissolution DNP-NMR: the impact of overexpressed membrane transporters.
http://www.bionmr.com//www.ncbi.nlm.nih.gov/corehtml/query/egifs/http:--media.wiley.com-assets-7315-19-Wiley_FullText_120x30_orange.png Related Articles Pyruvate cellular uptake and enzymatic conversion probed by dissolution DNP-NMR: the impact of overexpressed membrane transporters.
Magn Reson Chem. 2017 Jun;55(6):579-583
Authors: Balzan R, Fernandes L, Pidial L, Comment A, Tavitian B, Vasos PR
Abstract
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Proteomics Finding May Lead to Therapy Targeted at Cellular Pathway Linked to ALS - Genetic Engineering & Biotechnology News
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Proteomics Finding May Lead to Therapy Targeted at Cellular Pathway Linked to ALS
Genetic Engineering & Biotechnology News
Until the publication of this study, several mechanistic details of how the low-complexity domain of hnRNPA2 worked and how it changed into aggregates in disease were unknown, he says. Using nuclear magnetic resonance (NMR) spectroscopy, computer ...
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01-21-2018 05:03 PM
Pyruvate cellular uptake and enzymatic conversion probed by dissolution DNP-NMR: the impact of overexpressed membrane transporters
From The DNP-NMR Blog:
Pyruvate cellular uptake and enzymatic conversion probed by dissolution DNP-NMR: the impact of overexpressed membrane transporters
p.p1 {margin: 0.0px 0.0px 0.0px 36.0px; text-indent: -36.0px; font: 12.0px Helvetica}
Balzan, R., et al., Pyruvate cellular uptake and enzymatic conversion probed by dissolution DNP-NMR: the impact of overexpressed membrane transporters. Magn Reson Chem, 2017. 55(6): p. 579-583.
https://www.ncbi.nlm.nih.gov/pubmed/27859555
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09-29-2017 10:01 PM
The CopC Family: Structural and Bioinformatic Insightsinto a Diverse Group of Periplasmic Copper Binding Proteins
The CopC Family: Structural and Bioinformatic Insightsinto a Diverse Group of Periplasmic Copper Binding Proteins
http://pubs.acs.org/appl/literatum/publisher/achs/journals/content/bichaw/0/bichaw.ahead-of-print/acs.biochem.6b00175/20160406/images/medium/bi-2016-001758_0008.gif
Biochemistry
DOI: 10.1021/acs.biochem.6b00175
http://feeds.feedburner.com/~ff/acs/bichaw?d=yIl2AUoC8zA
http://feeds.feedburner.com/~r/acs/bichaw/~4/NhUil9uehKc
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