BioNMR
NMR aggregator & online community since 2003
BioNMR    
Learn or help to learn NMR - get free NMR books!
 

Go Back   BioNMR > NMR career > Job marketplace
Advanced Search



Jobs Groups Conferences Literature Pulse sequences Software forums Programs Sample preps Web resources BioNMR issues


Webservers
NMR processing:
MDD
NMR assignment:
Backbone:
Autoassign
MARS
UNIO Match
PINE
Side-chains:
UNIO ATNOS-Ascan
NOEs:
UNIO ATNOS-Candid
UNIO Candid
ASDP
Structure from NMR restraints:
Ab initio:
GeNMR
Cyana
XPLOR-NIH
ASDP
UNIO ATNOS-Candid
UNIO Candid
Fragment-based:
BMRB CS-Rosetta
Rosetta-NMR (Robetta)
Template-based:
GeNMR
I-TASSER
Refinement:
Amber
Structure from chemical shifts:
Fragment-based:
WeNMR CS-Rosetta
BMRB CS-Rosetta
Homology-based:
CS23D
Simshift
Torsion angles from chemical shifts:
Preditor
TALOS
Promega- Proline
Secondary structure from chemical shifts:
CSI (via RCI server)
TALOS
MICS caps, β-turns
d2D
PECAN
Flexibility from chemical shifts:
RCI
Interactions from chemical shifts:
HADDOCK
Chemical shifts re-referencing:
Shiftcor
UNIO Shiftinspector
LACS
CheckShift
RefDB
NMR model quality:
NOEs, other restraints:
PROSESS
PSVS
RPF scores
iCing
Chemical shifts:
PROSESS
CheShift2
Vasco
iCing
RDCs:
DC
Anisofit
Pseudocontact shifts:
Anisofit
Protein geomtery:
Resolution-by-Proxy
PROSESS
What-If
iCing
PSVS
MolProbity
SAVES2 or SAVES4
Vadar
Prosa
ProQ
MetaMQAPII
PSQS
Eval123D
STAN
Ramachandran Plot
Rampage
ERRAT
Verify_3D
Harmony
Quality Control Check
NMR spectrum prediction:
FANDAS
MestReS
V-NMR
Flexibility from structure:
Backbone S2
Methyl S2
B-factor
Molecular dynamics:
Gromacs
Amber
Antechamber
Chemical shifts prediction:
From structure:
Shiftx2
Sparta+
Camshift
CH3shift- Methyl
ArShift- Aromatic
ShiftS
Proshift
PPM
CheShift-2- Cα
From sequence:
Shifty
Camcoil
Poulsen_rc_CS
Disordered proteins:
MAXOCC
Format conversion & validation:
CCPN
From NMR-STAR 3.1
Validate NMR-STAR 3.1
NMR sample preparation:
Protein disorder:
DisMeta
Protein solubility:
camLILA
ccSOL
Camfold
camGroEL
Zyggregator
Isotope labeling:
UPLABEL
Solid-state NMR:
sedNMR


Reply
Thread Tools Search this Thread Rate Thread Display Modes
  #1  
Unread 08-10-2008, 02:37 PM
Junior Member
 
Join Date: Aug 2008
Posts: 2
Points: 24, Level: 1
Points: 24, Level: 1 Points: 24, Level: 1 Points: 24, Level: 1
Level up: 47%, 26 Points needed
Level up: 47% Level up: 47% Level up: 47%
Activity: 0%
Activity: 0% Activity: 0% Activity: 0%
NMR Credits: 0
NMR Points: 24
Downloads: 0
Uploads: 0
Default Postdoctoral position to study Protein-Protein Interactions and their role in Mechanisms of Signal Transduction using protein solution NMR/x-ray crystallography

Spincore.com are advertising a postdoc NMR position. It sounds pretty interesting.

"""

Postdoctoral position to study Protein-Protein Interactions and their role in Mechanisms of Signal Transduction using protein solution NMR /x-ray crystallography
Case Medical School, Cleveland, Ohio, USA


How are signaling events transmitted from one protein to another? To answer this question we are looking to add a postdoctoral co-workers to our interdisciplinary team. Our interest is to understand protein-protein interactions, protein structure and dynamics in the context of cell signaling mechanisms. {e.g. see our recent papers J.Biol.Chem.,282, 37215-37224 (2007), Structure 16, 246-258 (2008) and J.Mol.Biol. 377, 1474-87 (2008)}. The systems include several small GTPases and their interacting proteins, principally the cytoplasmic domains of plexins and of other receptors.

Research in protein biophysics/structural biology. We principally use solution NMR for protein structure determination, surface mapping and characterization of conformational change. The project may involve amide hydrogen exchange, NMR relaxation and molecular dynamics simulation as additional tools. NMR facilities at the Cleveland Center for Structural Biology consist of two 600 MHz, an 800 MHz and an 900 MHz Bruker spectrometers all with cryoprobes, making the Center one of the premier NMR facilities in the US. Apart from NMR, we employ other biophysical techniques including circular dichroism and fluorescence spectroscopy as well as isothermal titration calorimetry (ITC). Recently have started x-ray crystallography as a second major component to the laboratory (a Rigaku MicroMax-007 HF instrument with a 94x94mm CCD detector has recently been installed for crystal screening) and are also moving into cell biology.

We are looking for talented and motivated coworkers, who aim to become independent researchers/project leaders. Prior experience with protein NMR or x-ray crystallography is essential.. The Buck laboratory provides a stimulating but friendly working environment we are still relatively small & young, which has advantages. The Medical School of Case Western Reserve University is highly rated overall in the US (~ 13th in terms of NIH funding) and Cleveland is a pleasant but affordable place to live with excellent educational, medical and cultural institutions. Starting date, project details and salary are negotiable. Please check out our lab. page for further details at http://mbalster.case.edu/; if interested, please send your resume, overview of your scientific interests and career goals as well as contact details of three referees able to provide references by e-mail to Matthias.Buck@case.edu

"""
http://www.spincore.com/nmrjobs/pos08_22.html
Reply With Quote


Did you find this post helpful? Yes | No

Reply
Similar Threads
Thread Thread Starter Forum Replies Last Post
An NMR method to study protein-protein interactions.
An NMR method to study protein-protein interactions. An NMR method to study protein-protein interactions. Methods Mol Biol. 2012;757:129-37 Authors: Nishida N, Shimada I Abstract Specific interactions between proteins are a fundamental process underlying the various biological events, such as cell-cell contacts, signal transduction, and gene expression. Therefore, the structural investigations of protein-protein interactions provide useful information for understanding these events. We describe an NMR method, termed the cross-saturation...
nmrlearner Journal club 0 09-13-2011 08:27 PM
Modular protein-RNA interactions regulating mRNA metabolism: a role for NMR.
Modular protein-RNA interactions regulating mRNA metabolism: a role for NMR. Modular protein-RNA interactions regulating mRNA metabolism: a role for NMR. Eur Biophys J. 2011 Apr 7; Authors: Cukier CD, Ramos A Here we review the role played by transient interactions between multi-functional proteins and their RNA targets in the regulation of mRNA metabolism, and we describe the important function of NMR spectroscopy in the study of these systems. We place emphasis on a general approach for the study of different features of modular multi-domain...
nmrlearner Journal club 0 04-08-2011 10:00 AM
High-Pressure Protein Crystallography and NMR to Explore Protein Conformations.
High-Pressure Protein Crystallography and NMR to Explore Protein Conformations. High-Pressure Protein Crystallography and NMR to Explore Protein Conformations. Annu Rev Biophys. 2010 Jul 21; Authors: Collins MD, Kim CU, Gruner SM High-pressure methods for solving protein structures by X-ray crystallography and NMR are maturing. These techniques are beginning to impact our understanding of thermodynamic and structural features that define not only the protein's native conformation, but also the higher free energy conformations. The ability of...
nmrlearner Journal club 0 02-02-2011 02:40 AM
A View into the Blind Spot: Solution NMR Provides New Insights into Signal Transduction Across the Lipid Bilayer.
A View into the Blind Spot: Solution NMR Provides New Insights into Signal Transduction Across the Lipid Bilayer. Related Articles A View into the Blind Spot: Solution NMR Provides New Insights into Signal Transduction Across the Lipid Bilayer. Structure. 2010 Dec 8;18(12):1559-1569 Authors: Call ME, Chou JJ One of the most fundamental problems in cell biology concerns how cells communicate with their surroundings through surface receptors. The last few decades have seen major advances in understanding the mechanisms of receptor-ligand...
nmrlearner Journal club 0 12-08-2010 06:21 PM
Structure of key protein for cellular signal transduction elucidated - News-Medical.n
Structure of key protein for cellular signal transduction elucidated - News-Medical.net <img alt="" height="1" width="1" /> Structure of key protein for cellular signal transduction elucidated News-Medical.net Using NMR spectroscopy, Professor Michael Sattler and his team elucidated the spatial structure of the Qua1 region of Sam68, which is responsible for the ... and more &raquo; Read here
nmrlearner Online News 0 09-10-2010 12:58 PM
Postdoctoral Position "Solution Dynamics of Protein Kinases" in New York
Postdoctoral Position "Solution Dynamics of Protein Kinases" in New York A postdoctoral position to study the solution dynamics and structure of protein kinases is available on a NIH funded project (REF#: HS-R-6453-10-08-S). Our group is interested in how static and dynamic changes of protein structure affect the activity of protein kinases. We combine X-ray crystallography, NMR and ligand binding kinetics with collaborative molecular dynamic studies (See e.g. ref 1 and 2). Our research group is located at Stony Brook University in a highly interactive environment with the New York...
nmrlearner Job marketplace 0 08-21-2010 05:17 AM
Postdoctoral Position "Solution Dynamics of Protein Kinases" in New York
Postdoctoral Position "Solution Dynamics of Protein Kinases" in New York A postdoctoral position to study the solution dynamics and structure of protein kinases is available on a NIH funded project (REF#: HS-R-6453-10-08-S). Our group is interested in how static and dynamic changes of protein structure affect the activity of protein kinases. We combine X-ray crystallography, NMR and ligand binding kinetics with collaborative molecular dynamic studies (See e.g. ref 1 and 2). Our research group is located at Stony Brook University in a highly interactive environment with the New York...
nmrlearner Job marketplace 0 08-21-2010 05:14 AM
Postdoctoral Position in Solution and Solid State Protein NMR Spectroscopy, University of Guelph, Canada
Hello everybody. The University of Guelph are looking for somebody to research the NMR of membrane proteins and protein-protein interactions. It sounds quite interesting. (taken from the ICMRBS2008 website) http://www.icmrbs2008.org/Portals/0/postdoc_ssnmr.pdf
Cameron Job marketplace 0 09-21-2008 11:54 AM


Thread Tools Search this Thread
Search this Thread:

Advanced Search
Display Modes Rate This Thread
Rate This Thread:

Posting Rules
You may not post new threads
You may not post replies
You may not post attachments
You may not edit your posts

BB code is On
Smilies are On
[IMG] code is On
HTML code is On
Trackbacks are Off
Pingbacks are Off
Refbacks are Off



BioNMR advertisements to pay for website hosting and domain registration. Nobody does it for us.



Powered by vBulletin® Version 3.7.3
Copyright ©2000 - 2017, Jelsoft Enterprises Ltd.
Copyright, BioNMR.com, 2003-2013
Search Engine Friendly URLs by vBSEO 3.6.0

All times are GMT. The time now is 04:40 PM.


Map