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Postdocs, Students, Technician in RNA-protein NMR at CEITEC (Brno/CZ) |
Nov 06, 2012 - 10:32 AM - by peter.lukavsky
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Dear colleagues, the Lukavsky Lab has openings for two postdocs, students and one technician at CEITEC (Brno/CZ) to work on RNA-based regulation of gene expression. We are focused on understanding molecular principles of RNA-protein assemblies regulating gene expression at the posttranscriptional level. In the cytoplasm, gene expression is timely and spatially coordinated to ensure that proteins are produced at the right place and time in the cell. Failure to properly transport and localize mRNAs and to control protein expression can lead to impairment of memory formation, neurobiological diseases and cancer.
We plan to study regulatory RNA elements found in neuronal mRNAs important for learning, memory formation and neurobiological diseases and their interaction with protein partners. We put a strong focus on alternative splicing, mRNA transport and translational control.
Our main structural tool is NMR spectroscopy, which we have successfully applied to determine several structures of large, regulatory RNAs and complexes. Our structural work is always accompanied by biochemical and functional studies to gain profound insights how regulatory RNAs and their complexes function in the cell.
CEITEC is a vibrant work place, with excellent colleagues and infrastructure for structural biology including six high-field NMR instruments from 500 to 950 MHz equipped with cryo-probes.
Successful candidates should be highly motivated and creative and share our fascination for RNA structure and function. Previous experience in molecular biology, biophysics and biochemistry are a plus. Good communication and interpersonal skills and fluency in spoken and written English are required.
For contact: peter.lukavsky@ceitec.muni.cz
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0 Replies | 1,005 Views
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TWO FACULTY POSITIONS in MOLECULAR STRUCTURE & FUNCTION THE HOSPITAL FOR SICK CHILDREN, TORONTO, ON, CANADA |
Oct 15, 2012 - 5:50 PM - by markber
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TWO FACULTY POSITIONS in MOLECULAR STRUCTURE & FUNCTION
THE HOSPITAL FOR SICK CHILDREN, TORONTO, ON, CANADA
To coincide with the opening of The Hospital for Sick Children’s (SickKids) new
Centre for Research and Learning in August 2013, the Program in Molecular
Structure & Function (MSF) is seeking two exceptional individuals who are
interested in exploiting the unique research environment provided by Canada’s
largest paediatric hospital-based research institute (Sickkids - hospital
Research/AbouttheInstitute/index.html). Individuals, at all stages of their career,
that use biophysical, biochemical, computational and/or chemical biology tools to
study biological macromolecules or biochemical processes at the molecular level,
bridging in vitro to cellular and/or in vivo studies are encouraged to apply (http://
Job openings)
Preference will be given to candidates that enhance and complement the existing
research of Program members (http://www.sickkids.ca/Research/Molecular-
Structure-and-Function and http://www.sickkids.ca/Research/Molecular-Structure- ... [Read More]
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0 Replies | 1,141 Views
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