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Default PhD position in DNP methodology in Paris, France #DNPNMR

From The DNP-NMR Blog:

PhD position in DNP methodology in Paris, France #DNPNMR

A PhD position is available in the NMR group of the Laboratoire des biomolécule, located in the chemistry department of the Ecole Normale Supérieure in Paris, France.


Dynamic nuclear polarisation (DNP) techniques provide unprecedented NMR signal enhancement (by several orders of magnitude) and has made possible experiments that were until recently impossible to achieve by conventional methods. In conditions of very high polarisation, the interaction between the large sample magnetisation with the detection circuit leads to nonlinear behaviour (« radiation damping », maser effect, dipolar field effects).


Very unusual NMR signals have been observed in the solid state at liquid helium temperatures (~1.2 K), that exhibit typical multiple maser effects at short times (< ~100 ms) on the one hand, and persistence for tens of seconds on the other hand, (when solid-state NMR signals are typically expected to last no more than ~500 microsecond).


These signals reflect the combination between complex processes of different nature, involving nonlinearities of the magnetization dynamics and DNP.


The PhD student will in particular:


- contribute to the construction and the implementation of the maser control unit on both polarizers (6.7 T and 9.4 T) in use in the lab;


- perform controlled maser experiments in various experimental conditions in order to access the details of the DNP process;


- contribute to the analysis of the data using various models, through simulations or theoretical calculations;


- contribute to the application of the developed instrumentation to optimize hyperpolarization DNP sequences and their integration in dissolution-DNP experiments.


Applicants should preferably have a physics or chemical physics background (significant knowledge in quantum mechanics will be valued), with a strong interest for both fundamental and applied aspects of magnetic resonance.


The NMR team of the Laboratoire des biomolécules (located in part in the chemistry department at ENS-Paris) is strongly methodology-oriented, in various aspects of NMR. The group is equipped with a 800 MHz spectrometer (liqui/solid/micro-imaging), a 600 MHz spectrometer (liquid/high-resolution relaxometry and two-field NMR), a 400 MHz spectrometer (liquid /solid) and two polarizers for dissolution-DNP (6.7 T and 9.4 T)


The position is for 36 months, and the net monthly salary will be about 1400 €.To apply, please send a CV, a cover letter, and the names of two potential referees who could be contacted to provide a supporting letter, to Daniel Abergel (daniel.abergel@ens.fr)


A publication list of the team is available on the website http://www.paris-en-resonance.fr/


-- Daniel Abergel, MD, PhD Laboratoire des Biomolécules UMR7203 Département de Chimie Ecole Normale Supérieure 24, rue Lhomond, 75005 Paris Tel. : +33 1 44 32 32 65 email : daniel.abergel@ens.fr


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