NMR paper An NMR spectroscopic identity test for the control of the capsular polysaccharide fro

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[NMR paper] An NMR spectroscopic identity test for the control of the capsular polysaccharide fro

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NMR processing:

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NMR assignment:

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Side-chains:

NOEs:

Structure from NMR restraints:

Ab initio:

Fragment-based:

Rosetta-NMR (Robetta)

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Structure from chemical shifts:

Fragment-based:

Homology-based:

Torsion angles from chemical shifts:

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Promega- Proline

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TALOS

MICS caps, β-turns

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Poulsen_rc_CS

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11-19-2010, 08:29 PM

nmrlearner

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An NMR spectroscopic identity test for the control of the capsular polysaccharide fro

An NMR spectroscopic identity test for the control of the capsular polysaccharide from Haemophilus influenzae type b.

Related Articles An NMR spectroscopic identity test for the control of the capsular polysaccharide from Haemophilus influenzae type b.

Biologicals. 2000 Sep;28(3):175-83

Authors: Lemercinier X, Jones C

We describe the use of Nuclear Magnetic Resonance (NMR) spectroscopy to control the identity of purified bulk capsular polysaccharide [called poly(ribosylribitolphosphate) or PRP] from Haemophilus influenzae type b (Hib), and derivatised forms, used in the production of Hib polysaccharide-protein conjugate vaccines. We describe the approaches we have developed to validate this test.

PMID: 10964444 [PubMed - indexed for MEDLINE]

Source: PubMed

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