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[NMR paper] NMR Relaxation Dispersion Experiments to Study Phosphopeptide Recognition by SH2 Domains: The Grb2-SH2-Phosphopeptide Encounter Complex
Sep 06, 2023 - 1:37 AM - by nmrlearner
nmrlearner's Avatar NMR Relaxation Dispersion Experiments to Study Phosphopeptide Recognition by SH2 Domains: The Grb2-SH2-Phosphopeptide Encounter Complex

Protein interactions are at the essence of life. Proteins evolved not to have stable structures, but rather to be specialized in participating in a network of interactions. Every interaction involving proteins comprises the formation of an encounter complex, which may have two outcomes: (i) the dissociation or (ii) the formation of the final specific complex. Here, we present a methodology to characterize the encounter complex of the Grb2-SH2 domain with a phosphopeptide. This method can be...

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0 Replies | 219 Views
Future Scope of Protein Trends & Technologies Market Expects to See Significant Growth During 2023-2029 - openPR
Sep 05, 2023 - 4:51 AM - by nmrlearner
nmrlearner's Avatar Future Scope of Protein Trends & Technologies Market Expects to See Significant Growth During 2023-2029 openPR
Future Scope of Protein Trends & Technologies Market Expects to See Significant Growth During 2023-2029 - openPR
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0 Replies | 250 Views
Protein Crystallization and Crystallography Market 2023 Industry Growth Statistics, Gross Margins and For - Benzinga
Sep 05, 2023 - 4:51 AM - by nmrlearner
nmrlearner's Avatar Protein Crystallization and Crystallography Market 2023 Industry Growth Statistics, Gross Margins and For - Benzinga

Protein Crystallization and Crystallography Market 2023 Industry Growth Statistics, Gross Margins and For Benzinga Read here
0 Replies | 225 Views
Protein Allostery and NMR - News-Medical.Net
Sep 05, 2023 - 4:51 AM - by nmrlearner
nmrlearner's Avatar Protein Allostery and NMR - News-Medical.Net

Protein Allostery and NMR News-Medical.Net Read here
0 Replies | 177 Views
Espresso can prevent Alzheimer’s protein clum - EurekAlert
Sep 03, 2023 - 7:45 PM - by nmrlearner
nmrlearner's Avatar Espresso can prevent Alzheimer’s protein clum EurekAlert
Espresso can prevent Alzheimer’s protein clum - EurekAlert
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0 Replies | 249 Views
Structural insights into MIC2 recognition by MIC2-associated protein ... - Nature.com
Sep 02, 2023 - 1:54 AM - by nmrlearner
nmrlearner's Avatar Structural insights into MIC2 recognition by MIC2-associated protein ... - Nature.com

Structural insights into MIC2 recognition by MIC2-associated protein ... Nature.com Read here
0 Replies | 179 Views
[NMR paper] NMR structure verifies the eponymous zinc finger domain of transcription factor ZNF750
Sep 02, 2023 - 1:54 AM - by nmrlearner
nmrlearner's Avatar NMR structure verifies the eponymous zinc finger domain of transcription factor ZNF750

ZNF750 is a nuclear transcription factor that activates skin differentiation and has tumor suppressor roles in several cancers. Unusually, ZNF750 has only a single zinc-finger (ZNF) domain, Z*, with an amino acid sequence that differs markedly from the CCHH family consensus. Because of its sequence differences Z* is classified as degenerate, presumed to have lost the ability to bind the zinc ion required for folding. AlphaFold predicts an irregular structure for Z* with low confidence. Low...

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0 Replies | 226 Views
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