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Protein Characterization and Identification Market Size Envisions ... - GlobeNewswire
Sep 19, 2023 - 8:52 PM - by nmrlearner
nmrlearner's Avatar Protein Characterization and Identification Market Size Envisions ... - GlobeNewswire

Protein Characterization and Identification Market Size Envisions ... GlobeNewswire Read here
0 Replies | 175 Views
[NMR paper] Probing the Conformational Space of the Cannabinoid Receptor 2 and a Systematic Investigation of DNP-Enhanced MAS NMR Spectroscopy of Proteins in Detergent Micelles
Sep 19, 2023 - 8:52 PM - by nmrlearner
nmrlearner's Avatar Probing the Conformational Space of the Cannabinoid Receptor 2 and a Systematic Investigation of DNP-Enhanced MAS NMR Spectroscopy of Proteins in Detergent Micelles

Tremendous progress has been made in determining the structures of G-protein coupled receptors (GPCR) and their complexes in recent years. However, understanding activation and signaling in GPCRs is still challenging due to the role of protein dynamics in these processes. Here, we show how dynamic nuclear polarization (DNP)-enhanced magic angle spinning nuclear magnetic resonance in combination with a unique pair labeling approach can be used to study the conformational ensemble at specific...

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0 Replies | 391 Views
Mixed, nonclassical behavior in a classic allosteric protein ... - pnas.org
Sep 15, 2023 - 1:33 AM - by nmrlearner
nmrlearner's Avatar Mixed, nonclassical behavior in a classic allosteric protein ... - pnas.org

Mixed, nonclassical behavior in a classic allosteric protein ... pnas.org Read here
0 Replies | 214 Views
Protein Characterization and Identification Market Foreseen to Draw ... - Digital Journal
Sep 13, 2023 - 6:26 PM - by nmrlearner
nmrlearner's Avatar Protein Characterization and Identification Market Foreseen to Draw ... Digital Journal
Protein Characterization and Identification Market Foreseen to Draw ... - Digital Journal
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0 Replies | 172 Views
Protein Trends & Technologies Market Global Share Insights 2023-2030: Trends, Driving Factors, and Opport - Benzinga
Sep 11, 2023 - 10:06 PM - by nmrlearner
nmrlearner's Avatar Protein Trends & Technologies Market Global Share Insights 2023-2030: Trends, Driving Factors, and Opport Benzinga
Protein Trends & Technologies Market Global Share Insights 2023-2030: Trends, Driving Factors, and Opport - Benzinga
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0 Replies | 292 Views
[NMR paper] Three Decades of REDOR in Protein Science: A Solid-State NMR Technique for Distance Measurement and Spectral Editing
Sep 10, 2023 - 2:39 AM - by nmrlearner
nmrlearner's Avatar Three Decades of REDOR in Protein Science: A Solid-State NMR Technique for Distance Measurement and Spectral Editing

Solid-state NMR (ss-NMR) is a powerful tool to investigate noncrystallizable, poorly soluble molecular systems, such as membrane proteins, amyloids, and cell walls, in environments that closely resemble their physical sites of action. Rotational-echo double resonance (REDOR) is an ss-NMR methodology, which by reintroducing heteronuclear dipolar coupling under magic angle spinning conditions provides intramolecular and intermolecular distance restraints at the atomic level. In addition, REDOR can...

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0 Replies | 290 Views
[NMR paper] Improving Geometric Validation Metrics and Ensuring Consistency with Experimental Data through TrioSA: An NMR Refinement Protocol
Sep 10, 2023 - 2:39 AM - by nmrlearner
nmrlearner's Avatar Improving Geometric Validation Metrics and Ensuring Consistency with Experimental Data through TrioSA: An NMR Refinement Protocol

Protein model refinement a the crucial step in improving the quality of a predicted protein model. This study presents an NMR refinement protocol called TrioSA (torsion-angle and implicit-solvation-optimized simulated annealing) that improves the accuracy of backbone/side-chain conformations and the overall structural quality of proteins. TrioSA was applied to a subset of 3752 solution NMR protein structures accompanied by experimental NMR data: distance and dihedral angle restraints. We...

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0 Replies | 219 Views
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