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	Dynamically committed, uncommitted, and quenched states encoded in protein kinase A revealed by NMR spectroscopy - pnas.org Dynamically committed, uncommitted, and quenched states encoded in protein kinase A revealed by NMR spectroscopy - pnas.org Dynamically committed, uncommitted, and quenched states encoded in protein kinase A revealed by NMR spectroscopy pnas.org Read here nmrlearner	Today 05:10 PM by nmrlearner	0	3	Online News
	[NMR paper] Optimizing NMR fragment-based drug screening for membrane protein targets Optimizing NMR fragment-based drug screening for membrane protein targets NMR spectroscopy has played a pivotal role in fragment-based drug discovery by coupling detection of weak ligand-target binding with structural mapping of the binding site. Fragment-based screening by NMR has been successfully applied to many soluble protein targets, but only to a limited number of membrane proteins, despite the fact that many drug targets are membrane proteins. This is partly because of difficulties preparing membrane proteins for NMR-especially human membrane proteins-and... More... nmrlearner	Today 05:10 PM by nmrlearner	0	8	Journal club
	[NMR paper] --Backbone NMR resonance assignments for the VP1u N-terminal receptor-binding domain of the human parvovirus pathogen B19 --Backbone NMR resonance assignments for the VP1u N-terminal receptor-binding domain of the human parvovirus pathogen B19 Parvovirus B19 (B19V) is a human pathogen that is the causative agent of several diseases in infants and adults. Due to a lack of antivirals against this virus, treatment options are limited. The minor capsid protein of B19V has a unique N terminus, named VP1u, which is essential for infection. The VP1u encodes a receptor binding domain (RBD), necessary for host cell entry, and a phospholipase A2 (PLA (2) ) domain, crucial for endosomal escape during cellular... nmrlearner	Today 05:10 PM by nmrlearner	0	9	Journal club
	NMR Methods for Structural Characterization of Protein-Protein Complexes - Frontiers NMR Methods for Structural Characterization of Protein-Protein Complexes - Frontiers NMR Methods for Structural Characterization of Protein-Protein Complexes Frontiers Read here nmrlearner	Today 05:00 AM by nmrlearner	0	19	Online News
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