Cryo-EM structure of P. falciparum circumsporozoite protein with a vaccine-elicited antibody is stabilized by somatically mutated inter-Fab contacts - Science Advances

		BioNMR > NMR community > Online News
Cryo-EM structure of P. falciparum circumsporozoite protein with a vaccine-elicited antibody is stabilized by somatically mutated inter-Fab contacts - Science Advances

Webservers

NMR processing:

MDD

NMR assignment:

Backbone:

Side-chains:

NOEs:

Structure from NMR restraints:

Ab initio:

Fragment-based:

Rosetta-NMR (Robetta)

Template-based:

GeNMR

I-TASSER

Refinement:

Amber

Structure from chemical shifts:

Fragment-based:

Homology-based:

Torsion angles from chemical shifts:

Preditor

TALOS

Promega- Proline

Secondary structure from chemical shifts:

CSI (via RCI server)

TALOS

MICS caps, β-turns

d2D

PECAN

Flexibility from chemical shifts:

RCI

Interactions from chemical shifts:

HADDOCK

Chemical shifts re-referencing:

NMR model quality:

NOEs, other restraints:

Chemical shifts:

RDCs:

Pseudocontact shifts:

Protein geomtery:

SAVES2 or SAVES4

Quality Control Check

NMR spectrum prediction:

FANDAS

MestReS

V-NMR

Flexibility from structure:

Backbone S2

Methyl S2

B-factor

Molecular dynamics:

Gromacs

Amber

Antechamber

Chemical shifts prediction:

From structure:

Shiftx2

Sparta+

Camshift

CH3shift- Methyl

ArShift- Aromatic

ShiftS

Proshift

PPM

CheShift-2- Cα

From sequence:

Shifty

Camcoil

Poulsen_rc_CS

Disordered proteins:

MAXOCC

Format conversion & validation:

CCPN

From NMR-STAR 3.1

Validate NMR-STAR 3.1

NMR sample preparation:

Protein disorder:

DisMeta

Protein solubility:

Isotope labeling:

Solid-state NMR:

View First Unread

Thread Tools

Search this Thread

Rate Thread

Display Modes

03-30-2019, 05:11 AM

nmrlearner

Senior Member

Join Date: Jan 2005

Posts: 23,191

Points: 193,617, Level: 100

Level up: 0%, 0 Points needed

Activity: 50.7%

Last Achievements

Award-Showcase

NMR Credits: 0

NMR Points: 193,617

Downloads: 0

Uploads: 0

Cryo-EM structure of P. falciparum circumsporozoite protein with a vaccine-elicited antibody is stabilized by somatically mutated inter-Fab contacts - Science Advances

Cryo-EM structure of P. falciparum circumsporozoite protein with a vaccine-elicited antibody is stabilized by somatically mutated inter-Fab contacts - Science Advances

Cryo-EM structure of P. falciparum circumsporozoite protein with a vaccine-elicited antibody is stabilized by somatically mutated inter-Fab contacts Science AdvancesThe circumsporozoite protein (CSP) on the surface of Plasmodium falciparum sporozoites is important for parasite development, motility, and host hepatocyte ...

Read here

Did you find this post helpful?

Similar Threads
Thread	Thread Starter	Forum	Replies	Last Post
Zooming in on protons: Neutron structure of protein kinase A trapped in a product complex - Science Advances Zooming in on protons: Neutron structure of protein kinase A trapped in a product complex - Science Advances Zooming in on protons: Neutron structure of protein kinase A trapped in a product complex Science AdvancesThe question vis-à-vis the chemistry of phosphoryl group transfer catalyzed by protein kinases remains a major challenge. The neutron diffraction structure of the ... Read here	nmrlearner	Online News	0	03-24-2019 10:41 PM
Blind protein structure prediction using accelerated free-energy simulations - Science Advances Blind protein structure prediction using accelerated free-energy simulations - Science Advances Blind protein structure prediction using accelerated free-energy simulations Science AdvancesWe report a key proof of principle of a new acceleration method for predicting protein structures by molecular ... Read here	nmrlearner	Online News	0	03-24-2019 10:41 PM
Blind protein structure prediction using accelerated free-energy simulations - Science Advances Blind protein structure prediction using accelerated free-energy simulations - Science Advances Blind protein structure prediction using accelerated free-energy simulations Science AdvancesWe report a key proof of principle of a new acceleration method for predicting protein structures by molecular ... Read here	nmrlearner	Online News	0	01-07-2019 05:49 AM
[NMR paper] Carbohydrate-polypeptide contacts in the antibody receptor CD16A identified through solution NMR spectroscopy. Carbohydrate-polypeptide contacts in the antibody receptor CD16A identified through solution NMR spectroscopy. Carbohydrate-polypeptide contacts in the antibody receptor CD16A identified through solution NMR spectroscopy. Biochemistry. 2017 Jun 14;: Authors: Subedi GP, Falconer DJ, Barb AW Abstract Asparagine-linked carbohydrates (N-glycans) are a common modification of eukaryotic proteins that confer multiple properties including the essential stabilization of therapeutic monoclonal antibodies. Here we present a rapid and...	nmrlearner	Journal club	0	06-15-2017 03:37 PM
Advances in Cryo-Electron Microscopy Will Improve the Global Protein Crystallization and Crystallography Market ... - Yahoo Finance UK Advances in Cryo-Electron Microscopy Will Improve the Global Protein Crystallization and Crystallography Market ... - Yahoo Finance UK <img alt="" height="1" width="1"> Advances in Cryo-Electron Microscopy Will Improve the Global Protein Crystallization and Crystallography Market ... Yahoo Finance UK The report segments the global protein crystallography market based on technique employed, including X-ray crystallography, Electron crystallography, NMR spectroscopy, and others. The report also segments the global protein crystallization base on ... and more » Read here	nmrlearner	Online News	0	03-29-2016 01:43 AM
Advances in Cryo-Electron Microscopy Will Improve the Global Protein Crystallization and Crystallography Market ... - Business Wire (press release) Advances in Cryo-Electron Microscopy Will Improve the Global Protein Crystallization and Crystallography Market ... - Business Wire (press release) <img alt="" height="1" width="1"> Advances in Cryo-Electron Microscopy Will Improve the Global Protein Crystallization and Crystallography Market ... Business Wire (press release) The report segments the global protein crystallography market based on technique employed, including X-ray crystallography, Electron crystallography, NMR spectroscopy, and others. The report also segments the global protein crystallization base on ... and more...	nmrlearner	Online News	0	03-08-2016 03:00 AM
Tricky protein may help HIV vaccine development - Science Daily (press release) Tricky protein may help HIV vaccine development - Science Daily (press release) <img alt="" height="1" width="1" /> Tricky protein may help HIV vaccine development Science Daily (press release) ... x-ray crystallography and nuclear magnetic resonance (NMR) spectroscopy. That's where Duke's interdisciplinary team stepped in, solving the structure using protein engineering, sophisticated NMR and software specifically designed to run on limited ... Read here	nmrlearner	Online News	0	01-16-2014 09:15 AM
[NMR paper] Malaria parasite-inhibitory antibody epitopes on Plasmodium falciparum merozoite surf Malaria parasite-inhibitory antibody epitopes on Plasmodium falciparum merozoite surface protein-1(19) mapped by TROSY NMR. Related Articles Malaria parasite-inhibitory antibody epitopes on Plasmodium falciparum merozoite surface protein-1(19) mapped by TROSY NMR. Mol Biochem Parasitol. 2004 Nov;138(1):29-36 Authors: Morgan WD, Lock MJ, Frenkiel TA, Grainger M, Holder AA Plasmodium falciparum merozoite surface protein 1 (MSP1)(19), the C-terminal fragment of merozoite surface protein 1, is a leading candidate antigen for development of a...	nmrlearner	Journal club	0	11-24-2010 10:03 PM

« Previous Thread | Next Thread »

Posting Rules
You may not post new threads You may not post replies You may not post attachments You may not edit your posts BB code is On Smilies are On [IMG] code is On HTML code is On Trackbacks are Off Pingbacks are Off Refbacks are Off