Neural network folds proteins a million times faster than its competitors - Chemistry World

		BioNMR > NMR community > Online News
Neural network folds proteins a million times faster than its competitors - Chemistry World

Webservers

NMR processing:

MDD

NMR assignment:

Backbone:

Side-chains:

NOEs:

Structure from NMR restraints:

Ab initio:

Fragment-based:

Rosetta-NMR (Robetta)

Template-based:

GeNMR

I-TASSER

Refinement:

Amber

Structure from chemical shifts:

Fragment-based:

Homology-based:

Torsion angles from chemical shifts:

Preditor

TALOS

Promega- Proline

Secondary structure from chemical shifts:

CSI (via RCI server)

TALOS

MICS caps, β-turns

d2D

PECAN

Flexibility from chemical shifts:

RCI

Interactions from chemical shifts:

HADDOCK

Chemical shifts re-referencing:

NMR model quality:

NOEs, other restraints:

Chemical shifts:

RDCs:

Pseudocontact shifts:

Protein geomtery:

SAVES2 or SAVES4

Quality Control Check

NMR spectrum prediction:

FANDAS

MestReS

V-NMR

Flexibility from structure:

Backbone S2

Methyl S2

B-factor

Molecular dynamics:

Gromacs

Amber

Antechamber

Chemical shifts prediction:

From structure:

Shiftx2

Sparta+

Camshift

CH3shift- Methyl

ArShift- Aromatic

ShiftS

Proshift

PPM

CheShift-2- Cα

From sequence:

Shifty

Camcoil

Poulsen_rc_CS

Disordered proteins:

MAXOCC

Format conversion & validation:

CCPN

From NMR-STAR 3.1

Validate NMR-STAR 3.1

NMR sample preparation:

Protein disorder:

DisMeta

Protein solubility:

Isotope labeling:

Solid-state NMR:

Thread Tools

Search this Thread

Rate Thread

Display Modes

05-09-2019, 05:55 AM

nmrlearner

Senior Member

Join Date: Jan 2005

Posts: 23,226

Points: 193,617, Level: 100

Level up: 0%, 0 Points needed

Activity: 50.7%

Last Achievements

Award-Showcase

NMR Credits: 0

NMR Points: 193,617

Downloads: 0

Uploads: 0

Neural network folds proteins a million times faster than its competitors - Chemistry World

Neural network folds proteins a million times faster than its competitors Chemistry WorldDespite knowing next to nothing about chemistry or biology, a neural network can make a good stab at one of the toughest problems in biochemistry – predicting ...

Neural network folds proteins a million times faster than its competitors - Chemistry World
More...

Did you find this post helpful?

Similar Threads
Thread	Thread Starter	Forum	Replies	Last Post
Synthetic molecules fold up into abiotic proteins \| Research - Chemistry World Synthetic molecules fold up into abiotic proteins \| Research - Chemistry World Synthetic molecules fold up into abiotic proteins \| Research Chemistry WorldCompound that self-assembles into giant folded ring could help scientists design bespoke abiotic proteins. Read here	nmrlearner	Online News	0	04-18-2019 06:17 AM
[NMR paper] Protein Structural Information Derived from NMR Chemical Shift with the Neural Network Program TALOS-N. Protein Structural Information Derived from NMR Chemical Shift with the Neural Network Program TALOS-N. Protein Structural Information Derived from NMR Chemical Shift with the Neural Network Program TALOS-N. Methods Mol Biol. 2015;1260:17-32 Authors: Shen Y, Bax A Abstract Chemical shifts are obtained at the first stage of any protein structural study by NMR spectroscopy. Chemical shifts are known to be impacted by a wide range of structural factors, and the artificial neural network based TALOS-N program has been trained to...	nmrlearner	Journal club	0	12-17-2014 09:43 PM
Protein power - Chemistry World Protein power - Chemistry World http://www.bionmr.com//nt0.ggpht.com/news/tbn/iMgxVA4gFjehCM/6.jpg Chemistry World <img alt="" height="1" width="1" /> Protein power Chemistry World In addition, his laboratory employs cutting edge methods in protein engineering (computational protein design and directed evolution), structural biology (NMR spectroscopy and x-ray crystallograghy) and cell biology (imaging). What led you to a career ...	nmrlearner	Online News	0	07-06-2012 05:21 PM
A new spin on protein NMR - Chemistry World A new spin on protein NMR - Chemistry World http://nt3.ggpht.com/news/tbn/q-Z6L3ReA3SmYM/6.jpg Chemistry World <img alt="" height="1" width="1" /> A new spin on protein NMR Chemistry World The researchers have described a new technique for rapidly obtaining solid samples of protein for nuclear magnetic resonance interrogation without needing to crystallise the protein. The method, which combines solid-state NMR with ultracentrifugation, ...	nmrlearner	Online News	0	06-14-2011 02:30 PM
[NMR tweet] $1.294 million of Federal Government support sees a World-class Nuclear Magnetic Resonance facility come to Waurn Ponds http://bit.ly/hLnbWW $1.294 million of Federal Government support sees a World-class Nuclear Magnetic Resonance facility come to Waurn Ponds http://bit.ly/hLnbWW Published by deakinresearch (deakinresearch) on 2010-12-02T04:24:03Z Source: Twitter	nmrlearner	Twitter NMR	0	12-02-2010 04:33 AM
[NMR paper] RESCUE: an artificial neural network tool for the NMR spectral assignment of proteins RESCUE: an artificial neural network tool for the NMR spectral assignment of proteins. Related Articles RESCUE: an artificial neural network tool for the NMR spectral assignment of proteins. J Biomol NMR. 1999 Sep;15(1):15-26 Authors: Pons JL, Delsuc MA The assignment of the 1H spectrum of a protein or a polypeptide is the prerequisite for advanced NMR studies. We present here an assignment tool based on the artificial neural network technology, which determines the type of the amino acid from the chemical shift values observed in the 1H...	nmrlearner	Journal club	0	11-18-2010 08:31 PM
[NMR paper] Using neural network predicted secondary structure information in automatic protein N Using neural network predicted secondary structure information in automatic protein NMR assignment. Related Articles Using neural network predicted secondary structure information in automatic protein NMR assignment. J Chem Inf Comput Sci. 1997 Nov-Dec;37(6):1086-94 Authors: Choy WY, Sanctuary BC, Zhu G In CAPRI, an automated NMR assignment software package that was developed in our laboratory, both chemical shift values and coupling topologies of spin patterns are used in a procedure for amino acids recognition. By using a knowledge base of...	nmrlearner	Journal club	0	08-22-2010 05:08 PM
HIFI-NMR: 10 times faster than regular NMR High-Resolution Iterative Frequency Identification for NMR as a General Strategy for Multidimensional Data Collection Hamid R. Eghbalnia, Arash Bahrami, Marco Tonelli, Klaas Hallenga, and John L. Markley J. Am. Chem. Soc.; 2005; 127(36) pp 12528 - 12536 http://pubs.acs.org/isubscribe/journals/jacsat/127/i36/figures/ja052120in00001.gif Abstract: We describe a novel approach to the rapid collection and processing of multidimensional NMR data: "high-resolution iterative frequency identification for NMR" (HIFI-NMR). As with other reduced dimensionality approaches, HIFI-NMR collects...	nmrlearner	Journal club	0	09-07-2005 08:21 PM

« Previous Thread | Next Thread »

Posting Rules
You may not post new threads You may not post replies You may not post attachments You may not edit your posts BB code is On Smilies are On [IMG] code is On HTML code is On Trackbacks are Off Pingbacks are Off Refbacks are Off