NMR experiments on aligned samples of membrane proteins.
 

NMR experiments on aligned samples of membrane proteins.

Related Articles NMR experiments on aligned samples of membrane proteins.

Methods Enzymol. 2005;394:350-82

Authors: De Angelis AA, Jones DH, Grant CV, Park SH, Mesleh MF, Opella SJ

NMR methods can be used to determine the structures of membrane proteins. Lipids can be chosen so that protein-containing micelles, bicelles, or bilayers are available as samples. All three types of samples can be aligned weakly or strongly, depending on their rotational correlation time. Solution NMR methods can be used with weakly aligned micelle and small bicelle samples. Solid-state NMR methods can be used with mechanically aligned bilayer and magnetically aligned bicelle samples.

PMID: 15808228 [PubMed - indexed for MEDLINE]



Source: PubMed