Thread: NMR paper NMR diffusion and relaxation study of drug-protein interaction.
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Default NMR diffusion and relaxation study of drug-protein interaction.
NMR diffusion and relaxation study of drug-protein interaction.

Related Articles NMR diffusion and relaxation study of drug-protein interaction.

Spectrochim Acta A Mol Biomol Spectrosc. 1999 Aug;55A(9):1897-901

Authors: Luo RS, Liu ML, Mao XA

In this work, NMR diffusion and relaxation measurements are applied to the study of the interaction between the anti-inflammatory drug salicylate and the human serum albumin (HSA) in solutions. The self-diffusion coefficients and the spin-lattice relaxation rates of salicylate are measured as a function of the concentration. The dissociation constant, Kd, for drug/HSA complexes and the number of binding sites, n, are evaluated.

PMID: 10474906 [PubMed - indexed for MEDLINE]



Source: PubMed
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