The Residual Structure of Unfolded Proteins Was Elucidated From The Standard Deviation Of NMR Intensity Differences
Introduction Sensitive methods are necessary to identify the residual structure in an unfolded protein, which may be similar to the functionally native structure. Signal intensity in NMR experiments is useful for analyzing the line width for a dynamic structure; however, another contribution is contained. Methods Here, the signal-intensity difference along the sequence was used for probability to calculate the standard deviation. Results The relative values of the standard deviations were 0.57,...
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