Thread: NMR paper NMR Investigations of Protein-Carbohydrate Interactions: The Recognition of Glycans by Galectins Engineered with Fluorotryptophan Residues
View Single Post
  #1  
Unread 11-08-2022, 02:21 AM
nmrlearner's Avatar
nmrlearner nmrlearner is offline
Senior Member
  
Join Date: Jan 2005
Posts: 23,212
Points: 193,617, Level: 100
Points: 193,617, Level: 100 Points: 193,617, Level: 100 Points: 193,617, Level: 100
Level up: 0%, 0 Points needed
Level up: 0% Level up: 0% Level up: 0%
Activity: 50.7%
Activity: 50.7% Activity: 50.7% Activity: 50.7%
Last Achievements
Award-Showcase
NMR Credits: 0
NMR Points: 0
Downloads: 0
Uploads: 0
Default NMR Investigations of Protein-Carbohydrate Interactions: The Recognition of Glycans by Galectins Engineered with Fluorotryptophan Residues
NMR Investigations of Protein-Carbohydrate Interactions: The Recognition of Glycans by Galectins Engineered with Fluorotryptophan Residues

Fluorine ( 19 F) incorporation into glycan binding proteins (lectins) has been achieved and exploited to monitor the binding to carbohydrate ligands by Nuclear Magnetic Resonance (NMR) Spectroscopy. Galectins are a family of lectins that bind carbohydrates, generally with weak affinities, through a combination of intermolecular interactions including a key CH-? stacking interaction involving a conserved Trp residue. Herein, two galectins, Galectin-3 (Gal3) and Galectin-8 (Gal8) with one and two...

More...
Reply With Quote

Did you find this post helpful? Yes | No