Thread: NMR paper NMR resonance assignment of the N-terminal GTPase domain of human Miro2 Bound to GTP
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Unread 09-03-2022, 03:47 AM
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Default NMR resonance assignment of the N-terminal GTPase domain of human Miro2 Bound to GTP
NMR resonance assignment of the N-terminal GTPase domain of human Miro2 Bound to GTP

Miro2 and Miro1 are mitochondrial-associated proteins critical for regulating mitochondrial movement within the cell. Both Miro1 and Miro2 have roles in promoting neuron function, but recently Miro2 has been shown to have additional roles in response to nutrient starvation in tumor cells. Miro1 and 2 consist of two small GTPase domains flanking a pair of EF-hands. The N-terminal GTPase (nGTPase) domain is responsible for initiating mitochondrial trafficking and interactions with GCN1 in prostate...

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