Thread: Solution NMR structure of Se0862, a highly conserved cyanobacterial protein involved in biofilm formation
View Single Post
  #1  
Unread 10-25-2020, 01:39 PM
nmrlearner's Avatar
nmrlearner nmrlearner is offline
Senior Member
  
Join Date: Jan 2005
Posts: 23,198
Points: 193,617, Level: 100
Points: 193,617, Level: 100 Points: 193,617, Level: 100 Points: 193,617, Level: 100
Level up: 0%, 0 Points needed
Level up: 0% Level up: 0% Level up: 0%
Activity: 50.7%
Activity: 50.7% Activity: 50.7% Activity: 50.7%
Last Achievements
Award-Showcase
NMR Credits: 0
NMR Points: 0
Downloads: 0
Uploads: 0
Default Solution NMR structure of Se0862, a highly conserved cyanobacterial protein involved in biofilm formation
Solution NMR structure of Se0862, a highly conserved cyanobacterial protein involved in biofilm formation

Abstract

Biofilms are accumulations of microorganisms embedded in extracellular matrices that protect against external factors and stressful environments. Cyanobacterial biofilms are ubiquitous and have potential for treatment of wastewater and sustainable production of biofuels. But the underlying mechanisms regulating cyanobacterial biofilm formation are unclear. Here, we report the solution NMR structure of a protein, Se0862, conserved across diverse cyanobacterial species and involved in regulation of biofilm formation in the cyanobacterium Synechococcus elongatus PCC 7942. Se0862 is a class ?+? protein with ???????? topology and roll architecture, consisting of a four-stranded ?-sheet that is flanked by four ?-helices on one side. Conserved surface residues constitute a hydrophobic pocket and charged regions that are likely also present in Se0862 orthologs.



More...
Reply With Quote

Did you find this post helpful? Yes | No