Thread: NMR paper NMR assignments of the C-terminal domain of human galectin-8.
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Default NMR assignments of the C-terminal domain of human galectin-8.
NMR assignments of the C-terminal domain of human galectin-8.

Related Articles NMR assignments of the C-terminal domain of human galectin-8.

Biomol NMR Assign. 2015 Oct;9(2):427-30

Authors: Liu CH, Chien CT, Lin CH, Hsu ST

Abstract
Galectins recognize ?-galectosides to promote a variety of cellular functions. Despite their sequence variations, all galectins share the same carbohydrate recognition domains (CRD) and their modes of ligand recognition at a structural level are essentially identical. Human galectin 8 plays an important role in numerous cancer and immune responses. It consists of two CRDs that are connected via a flexible linker. The substrate affinities and specificities of the N- and C-terminal domains are quite different. In order to investigate the structural basis of their substrate specificities, we complete the NMR (1)H, (13)C, and (15)N chemical shift assignments of C-terminal domain of human galectin-8 (hG8C).


PMID: 26126590 [PubMed - indexed for MEDLINE]



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