Thread: Dynamic nuclear polarization of biocompatible (13)C-enriched carbonates for in vivo pH imaging #DNPNMR
View Single Post
  #1  
Unread 06-02-2016, 02:11 AM
nmrlearner's Avatar
nmrlearner nmrlearner is offline
Senior Member
  
Join Date: Jan 2005
Posts: 23,197
Points: 193,617, Level: 100
Points: 193,617, Level: 100 Points: 193,617, Level: 100 Points: 193,617, Level: 100
Level up: 0%, 0 Points needed
Level up: 0% Level up: 0% Level up: 0%
Activity: 50.7%
Activity: 50.7% Activity: 50.7% Activity: 50.7%
Last Achievements
Award-Showcase
NMR Credits: 0
NMR Points: 0
Downloads: 0
Uploads: 0
Default Dynamic nuclear polarization of biocompatible (13)C-enriched carbonates for in vivo pH imaging #DNPNMR
From The DNP-NMR Blog:

Dynamic nuclear polarization of biocompatible (13)C-enriched carbonates for in vivo pH imaging #DNPNMR


Korenchan, D.E., et al., Dynamic nuclear polarization of biocompatible (13)C-enriched carbonates for in vivo pH imaging. Chem Commun (Camb), 2016. 52(14): p. 3030-3.


http://www.ncbi.nlm.nih.gov/pubmed/26792559


A hyperpolarization technique using carbonate precursors of biocompatible molecules was found to yield high concentrations of hyperpolarized (13)C bicarbonate in solution. This approach enabled large signal gains for low-toxicity hyperpolarized (13)C pH imaging in a phantom and in vivo in a murine model of prostate cancer.


Go to The DNP-NMR Blog for more info.
Reply With Quote

Did you find this post helpful? Yes | No