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Default Proteinâ??protein interaction inhibitor tackles drug resistance - Nature.com

Proteinâ??protein interaction inhibitor tackles drug resistance - Nature.com


Nature.com


Proteinâ??protein interaction inhibitor tackles drug resistance
Nature.com
NMR spectroscopy was then used to determine the mechanism of action of the most potent compound, termed iKIX1. The high-resolution structure showed that iKIX1 binds to the three-helix hydrophobic groove of the KIX domain of Gal11A, engaging the same ...


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