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Default Proteome-wide profiling of protein assemblies by cross-linking mass spectrometry - Nature.com

Proteome-wide profiling of protein assemblies by cross-linking mass spectrometry - Nature.com


Nature.com


Proteome-wide profiling of protein assemblies by cross-linking mass spectrometry
Nature.com
We describe an integrated workflow that robustly identifies cross-links from endogenous protein complexes in human cellular lysates. Our approach is based on the application of mass spectrometry (MS)-cleavable cross-linkers, sequential collision ...


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