Thread: NMR paper Conformational Ensembles in GPCR Activation.
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Unread 02-05-2013, 09:51 PM
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Default Conformational Ensembles in GPCR Activation.
Conformational Ensembles in GPCR Activation.

Related Articles Conformational Ensembles in GPCR Activation.

Cell. 2013 Jan 31;152(3):385-6

Authors: Vardy E, Roth BL

Abstract
Recent advances in G-protein-coupled receptor structural biology have provided only limited insight into the active conformations of these key signaling molecules. A paper from Nygaard et*al. reveals the dynamic nature of GPCRs along the activation pathway by complementing NMR experiments with ultralong-timescale molecular dynamics simulations.


PMID: 23374334 [PubMed - in process]



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