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The power and pitfalls of AlphaFold2 for structure prediction beyond rigid globular proteins - Nature.com
Jun 25, 2024 - 1:14 PM - by nmrlearner
nmrlearner's Avatar The power and pitfalls of AlphaFold2 for structure prediction beyond rigid globular proteins - Nature.com

The power and pitfalls of AlphaFold2 for structure prediction beyond rigid globular proteins Nature.com Read here
0 Replies | 6 Views
2?-19F labelling of ribose in RNAs: a tool to analyse RNA/protein interactions by NMR in physiological conditions - Frontiers
Jun 25, 2024 - 1:14 PM - by nmrlearner
nmrlearner's Avatar 2?-19F labelling of ribose in RNAs: a tool to analyse RNA/protein interactions by NMR in physiological conditions - Frontiers

2?-19F labelling of ribose in RNAs: a tool to analyse RNA/protein interactions by NMR in physiological conditions Frontiers Read here
0 Replies | 5 Views
Deep Neural Networks for Methyl NMR Spectroscopy of Large Proteins - MSN
Jun 25, 2024 - 1:02 AM - by nmrlearner
nmrlearner's Avatar Deep Neural Networks for Methyl NMR Spectroscopy of Large Proteins - MSN

Deep Neural Networks for Methyl NMR Spectroscopy of Large Proteins MSN Read here
0 Replies | 13 Views
The molecular basis for protein kinase A anchoring revealed by solution NMR - Nature.com
Jun 24, 2024 - 8:10 AM - by nmrlearner
nmrlearner's Avatar The molecular basis for protein kinase A anchoring revealed by solution NMR - Nature.com

The molecular basis for protein kinase A anchoring revealed by solution NMR Nature.com Read here
0 Replies | 29 Views
[NMR paper] NMR resonance assignment of the cell death execution domain BELL2 from multicellular bacterial signalosomes
Jun 23, 2024 - 10:40 AM - by nmrlearner
nmrlearner's Avatar NMR resonance assignment of the cell death execution domain BELL2 from multicellular bacterial signalosomes

Signalosomes are high-order protein machineries involved in complex mechanisms controlling regulated immune defense and cell death execution. The immune response is initiated by the recognition of exogeneous or endogenous signals, triggering the signalosome assembly process. The final step of signalosome fate often involves membrane-targeting and activation of pore-forming execution domains, leading to membrane disruption and ultimately cell death. Such cell death-inducing domains have been...

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0 Replies | 76 Views
Opportunities and Challenges of Backbone, Sidechain, and RDC Experiments to Study Membrane Protein Dynamics in ... - Frontiers
Jun 22, 2024 - 10:23 AM - by nmrlearner
nmrlearner's Avatar Opportunities and Challenges of Backbone, Sidechain, and RDC Experiments to Study Membrane Protein Dynamics in ... - Frontiers

Opportunities and Challenges of Backbone, Sidechain, and RDC Experiments to Study Membrane Protein Dynamics in ... Frontiers Read here
0 Replies | 38 Views
[NMR paper] Backbone NMR resonance assignments for the VP1u N-terminal receptor-binding domain of the human parvovirus pathogen B19
Jun 21, 2024 - 10:12 PM - by nmrlearner
nmrlearner's Avatar Backbone NMR resonance assignments for the VP1u N-terminal receptor-binding domain of the human parvovirus pathogen B19

Parvovirus B19 (B19V) is a human pathogen that is the causative agent of several diseases in infants and adults. Due to a lack of antivirals against this virus, treatment options are limited. The minor capsid protein of B19V has a unique N terminus, named VP1u, which is essential for infection. The VP1u encodes a receptor binding domain (RBD), necessary for host cell entry, and a phospholipase A2 (PLA(2)) domain, crucial for endosomal escape during cellular trafficking. Both domains are...

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0 Replies | 35 Views
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