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Insights Into the Structure and Function of the “Immortality Protein” - Technology Networks
Sep 24, 2020 - 7:17 PM - by nmrlearner
nmrlearner's Avatar Insights Into the Structure and Function of the “Immortality Protein” - Technology Networks

Insights Into the Structure and Function of the “Immortality Protein” Technology Networks Read here
0 Replies | 4 Views
Global Protein Crystallization & Crystallography Market Is Expected to Reach USD 1.97 Billion by 2027 : Fior Markets - Yahoo Finance
Sep 24, 2020 - 7:17 PM - by nmrlearner
nmrlearner's Avatar Global Protein Crystallization & Crystallography Market Is Expected to Reach USD 1.97 Billion by 2027 : Fior Markets - Yahoo Finance

Global Protein Crystallization & Crystallography Market Is Expected to Reach USD 1.97 Billion by 2027 : Fior Markets Yahoo Finance Read here
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Global Protein Crystallography Market Analysis By Distribution Channel, Significant Growth, Region, Top Countries Outlook And Forecast From 2021-2026 - Crypto Daily
Sep 24, 2020 - 7:17 PM - by nmrlearner
nmrlearner's Avatar Global Protein Crystallography Market Analysis By Distribution Channel, Significant Growth, Region, Top Countries Outlook And Forecast From 2021-2026 - Crypto Daily

Global Protein Crystallography Market Analysis By Distribution Channel, Significant Growth, Region, Top Countries Outlook And Forecast From 2021-2026 Crypto Daily Read here
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[NMR paper] (protein) AND nmr; +108 new citations
Sep 24, 2020 - 7:17 PM - by nmrlearner
nmrlearner's Avatar (protein) AND nmr; +108 new citations

108 new pubmed citations were retrieved for your search.Click on the search hyperlink below to display the complete search results:

... [Read More]
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[NMR paper] Intracellular binding/unbinding kinetics of approved drugs to carbonic anhydrase II observed by in-cell NMR.
Sep 24, 2020 - 7:17 PM - by nmrlearner
nmrlearner's Avatar Intracellular binding/unbinding kinetics of approved drugs to carbonic anhydrase II observed by in-cell NMR.

Related Articles Intracellular binding/unbinding kinetics of approved drugs to carbonic anhydrase II observed by in-cell NMR.

ACS Chem Biol. 2020 Sep 21;:

Authors: Luchinat E, Barbieri L, Cremonini M, Nocentini A, Supuran CT, Banci L

Abstract
Candidate drugs rationally designed in vitro often fail due to low efficacy in vivo caused by low tissue availability or because of unwanted side effects. To overcome the limitations of in vitro rational drug design, the binding of candidate drugs to their target needs to be evaluated in the cellular context. Here, we applied in-cell NMR to investigate the binding of a set of approved drugs to the isoform II of carbonic anhydrase (CA) in living human cells. Some compounds were originally developed towards other targets, and were later found to inhibit CAs. We observed strikingly different dose- and time-dependent binding, wherein some drugs exhibited a more complex behavior than others. Specifically, some compounds were... [Read More]
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