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Relationships Between Disease Severity and the C-reactive Protein ... - Cureus
Aug 25, 2023 - 2:40 PM - by nmrlearner
nmrlearner's Avatar Relationships Between Disease Severity and the C-reactive Protein ... - Cureus

Relationships Between Disease Severity and the C-reactive Protein ... Cureus Read here
0 Replies | 185 Views
[NMR paper] Illuminating GPCR signaling mechanisms by NMR spectroscopy with stable-isotope labeled receptors
Aug 25, 2023 - 2:40 PM - by nmrlearner
nmrlearner's Avatar Illuminating GPCR signaling mechanisms by NMR spectroscopy with stable-isotope labeled receptors

G protein-coupled receptors (GPCRs) exhibit remarkable structural plasticity, which underlies their capacity to recognize a wide range of extracellular molecules and interact with intracellular partner proteins. Nuclear magnetic resonance (NMR) spectroscopy is uniquely well-suited to investigate GPCR structural plasticity, enabled by stable-isotope "probes" incorporated into receptors that inform on structure and dynamics. Progress with stable-isotope labeling methods in Eukaryotic expression...

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0 Replies | 228 Views
Deciphering the molecular dynamics of complex proteins - Science Daily
Aug 23, 2023 - 10:11 AM - by nmrlearner
nmrlearner's Avatar Deciphering the molecular dynamics of complex proteins - Science Daily

Deciphering the molecular dynamics of complex proteins Science Daily Read here
0 Replies | 186 Views
SARS-CoV-2: The grasping fingers of the viral N protein - EurekAlert
Aug 23, 2023 - 10:11 AM - by nmrlearner
nmrlearner's Avatar SARS-CoV-2: The grasping fingers of the viral N protein EurekAlert
SARS-CoV-2: The grasping fingers of the viral N protein - EurekAlert
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0 Replies | 175 Views
Protein Crystallization And Crystallography Market: Segmented: Outlook 2030: Industry Insights & Opportunity Evaluation, 2019-2030 - Yahoo Finance
Aug 23, 2023 - 10:11 AM - by nmrlearner
nmrlearner's Avatar Protein Crystallization And Crystallography Market: Segmented: Outlook 2030: Industry Insights & Opportunity Evaluation, 2019-2030 Yahoo Finance
Protein Crystallization And Crystallography Market: Segmented: Outlook 2030: Industry Insights & Opportunity Evaluation, 2019-2030 - Yahoo Finance
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0 Replies | 187 Views
[NMR paper] Rapid Determination of the Topology of Oligomeric ?-Helical Membrane Proteins by Water- and Lipid-Edited Methyl NMR
Aug 23, 2023 - 10:11 AM - by nmrlearner
nmrlearner's Avatar Rapid Determination of the Topology of Oligomeric ?-Helical Membrane Proteins by Water- and Lipid-Edited Methyl NMR

Single-span oligomeric ?-helical transmembrane proteins are common in virus ion channels, which are targets of antiviral drugs. Knowledge about the high-resolution structures of these oligomeric ?-helical bundles is so far scarce. Structure determination of these membrane proteins by solid-state NMR traditionally requires resolving and assigning protein chemical shifts and measuring many interhelical distances, which are time-consuming. To accelerate experimental structure determination, here we...

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0 Replies | 323 Views
Mega-scale experimental analysis of protein folding stability in ... - Nature.com
Aug 21, 2023 - 7:58 PM - by nmrlearner
nmrlearner's Avatar Mega-scale experimental analysis of protein folding stability in ... - Nature.com

Mega-scale experimental analysis of protein folding stability in ... Nature.com Read here
0 Replies | 199 Views
[NMR paper] Expression and purification of Drosophila OBP44a with the aids of LC-MS and NMR
Aug 21, 2023 - 7:58 PM - by nmrlearner
nmrlearner's Avatar Expression and purification of Drosophila OBP44a with the aids of LC-MS and NMR

The production of highly purified native soluble proteins in large quantities is crucial for studying protein structure and function. Odorant binding proteins (OBPs) are small, soluble, extracellular proteins with multiple disulfide bonds, whose functions include, but are not limited to, binding hydrophobic molecules and delivering them to their corresponding receptors expressed on insect olfactory receptor neurons. Expression of proteins with multiple disulfide bonds like OBPs usually results...

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0 Replies | 268 Views
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