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[NMR paper] Solution NMR Analysis of O-Glycopeptide-Antibody Interaction |
Feb 16, 2024 - 7:14 AM - by nmrlearner
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Solution NMR Analysis of O-Glycopeptide-Antibody Interaction
O-Linked glycans potentially play a functional role in cellular recognition events. Recent structural analyses suggest that O-glycosylation can be a specific signal for a lectin receptor which recognizes both the O-glycan and the adjacent polypeptide region. Further, certain antibodies specifically bind to the O-glycosylated peptide. There is growing interest in the mechanism by which O-glycans on proteins are specifically recognized by lectins and antibodies. The recognition system may be...
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