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-   -   Detect protein disorder to avoid wasting NMR time (http://www.bionmr.com/forum/proteins-19/detect-protein-disorder-avoid-wasting-nmr-time-113/)

nmrlearner 08-15-2005 12:50 AM

Unless disordered proteins is what you are after, you may want to check if the protein you want to study with NMR is actually disordered and most likely not a very good NMR target.


The following servers for prediction of disordered regions in proteins are available.Relevant reference:

Addressing the intrinsic disorder bottleneck in structural proteomics.

Oldfield CJ, Ulrich EL, Cheng Y, Dunker AK, Markley JL.

Center for Eukaryotic Structural Genomics, Biochemistry Department, University of Wisconsin, Madison, Wisconsin 53706, USA.

Proteins. 2005 May 15;59(3):444-53


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