Protein discovery to aid HIV vaccine development - Jagran Post

		BioNMR > NMR community > Online News
Protein discovery to aid HIV vaccine development - Jagran Post

Webservers

NMR processing:

MDD

NMR assignment:

Backbone:

Side-chains:

NOEs:

Structure from NMR restraints:

Ab initio:

Fragment-based:

Rosetta-NMR (Robetta)

Template-based:

GeNMR

I-TASSER

Refinement:

Amber

Structure from chemical shifts:

Fragment-based:

Homology-based:

Torsion angles from chemical shifts:

Preditor

TALOS

Promega- Proline

Secondary structure from chemical shifts:

CSI (via RCI server)

TALOS

MICS caps, β-turns

d2D

PECAN

Flexibility from chemical shifts:

RCI

Interactions from chemical shifts:

HADDOCK

Chemical shifts re-referencing:

NMR model quality:

NOEs, other restraints:

Chemical shifts:

RDCs:

Pseudocontact shifts:

Protein geomtery:

SAVES2 or SAVES4

Quality Control Check

NMR spectrum prediction:

FANDAS

MestReS

V-NMR

Flexibility from structure:

Backbone S2

Methyl S2

B-factor

Molecular dynamics:

Gromacs

Amber

Antechamber

Chemical shifts prediction:

From structure:

Shiftx2

Sparta+

Camshift

CH3shift- Methyl

ArShift- Aromatic

ShiftS

Proshift

PPM

CheShift-2- Cα

From sequence:

Shifty

Camcoil

Poulsen_rc_CS

Disordered proteins:

MAXOCC

Format conversion & validation:

CCPN

From NMR-STAR 3.1

Validate NMR-STAR 3.1

NMR sample preparation:

Protein disorder:

DisMeta

Protein solubility:

Isotope labeling:

Solid-state NMR:

View First Unread

Thread Tools

Search this Thread

Rate Thread

Display Modes

01-14-2014, 03:20 PM

nmrlearner

Senior Member

Join Date: Jan 2005

Posts: 23,174

Points: 193,617, Level: 100

Level up: 0%, 0 Points needed

Activity: 50.7%

Last Achievements

Award-Showcase

NMR Credits: 0

NMR Points: 193,617

Downloads: 0

Uploads: 0

Protein discovery to aid HIV vaccine development - Jagran Post

Protein discovery to aid HIV vaccine development - Jagran Post

Jagran Post

Protein discovery to aid HIV vaccine development
Jagran Post
Duke researchers solved the structure using protein engineering, sophisticated NMR and software specifically designed to run on limited data. First author Patrick Reardon engineered a protein that incorporated the HIV MPER, associated with a membrane ...
Tricky protein may help HIV vaccine developmentR & D Magazine

all 11 news articles »
Read here

Did you find this post helpful?

Similar Threads
Thread	Thread Starter	Forum	Replies	Last Post
USA: Protein discovery to aid HIV vaccine development - IBNLive http://www.bionmr.com//t0.gstatic.com/images?q=tbn:ANd9GcQl3PB70ArSCLTtWvAe0Fbbi8DAx6nt4UHLpCFZ0iDGh6inuvUX21TtV_vkeuk4Bt6-rc_cExo IBNLive <img alt="" height="1" width="1" /> USA: Protein discovery to aid HIV vaccine development IBNLive determination techniques, such as x-ray crystallography and nuclear magnetic resonance (NMR) spectroscopy. Duke researchers solved the structure using protein engineering, sophisticated NMR and software specifically designed to run on limited data. Protein discovery to aid HIV vaccine developmentJagran Post Tricky protein may help HIV vaccine...	nmrlearner	Online News	0	01-14-2014 03:20 PM
Tricky protein may help HIV vaccine development - R & D Magazine Tricky protein may help HIV vaccine development - R & D Magazine http://www.bionmr.com//t0.gstatic.com/images?q=tbn:ANd9GcQ8Kojmo3kFcA2JO9Fb2fCSZ0SDvF60sytOe8KpEV_k6ZkfkV0AP1v_9D0fD6kNMcfPXXXmFKQ R & D Magazine <img alt="" height="1" width="1" /> Tricky protein may help HIV vaccine development R & D Magazine ... x-ray crystallography and nuclear magnetic resonance (NMR) spectroscopy. That's where Duke's interdisciplinary team stepped in, solving the structure using protein engineering, sophisticated NMR and software specifically designed to run on limited ... and more »	nmrlearner	Online News	0	01-14-2014 02:57 AM
In vivo Imaging Fluorescent Proteins Expressed from DNA Vaccine Constructs - News-Medical.net In vivo Imaging Fluorescent Proteins Expressed from DNA Vaccine Constructs - News-Medical.net <img alt="" height="1" width="1" /> In vivo Imaging Fluorescent Proteins Expressed from DNA Vaccine Constructs News-Medical.net Nevertheless, most of the clinical trials that reported the use of these proteins have used recombinant viruses; injected cells expressing the proteins; or used recombinant protein in an artificial mouse. This article examines the technique used to ... Read here	nmrlearner	Online News	0	12-17-2013 01:46 PM
New Protein Evolution Insight Could Improve Drug Design - Drug Discovery & Development <img alt="" height="1" width="1" /> New Protein Evolution Insight Could Improve Drug Design Drug Discovery & Development The team used a variety of techniques to characterize the two versions of the enzyme, including X-ray crystallography and nuclear magnetic resonance, analyses of DHFR amino-acid sequences and evaluations of the enzyme's functionality in cells and in ... and more » New Protein Evolution Insight Could Improve Drug Design - Drug Discovery & Development More...	nmrlearner	Online News	0	10-01-2013 09:43 AM
[NMR paper] Structural characterization by NMR of a double phosphorylated chimeric Peptide vaccine for treatment of Alzheimer's disease. Structural characterization by NMR of a double phosphorylated chimeric Peptide vaccine for treatment of Alzheimer's disease. Structural characterization by NMR of a double phosphorylated chimeric Peptide vaccine for treatment of Alzheimer's disease. Molecules. 2013;18(5):4929-41 Authors: Ramírez-Gualito K, Richter M, Matzapetakis M, Singer D, Berger S Abstract Rational design of peptide vaccines becomes important for the treatment of some diseases such as Alzheimer's disease (AD) and related disorders. In this study, as part of a larger...	nmrlearner	Journal club	0	04-30-2013 10:21 PM
Insights into protein folding may lead to better flu vaccine - R & D Magazine Insights into protein folding may lead to better flu vaccine - R & D Magazine <img alt="" height="1" width="1" /> Insights into protein folding may lead to better flu vaccine R & D Magazine The method, described online in the Proceedings of the National Academy of Sciences July 16, allows researchers to take snapshots of the cell's protein-making machineryâ??called ribosomesâ??in various stages of protein production. The scientists then ... Read here	nmrlearner	Online News	0	07-27-2012 11:58 AM
Researchers Look at Averting Drug Resistance - Drug Discovery & Development <img alt="" height="1" width="1" /> Researchers Look at Averting Drug Resistance Drug Discovery & Development Kern and her team studied the protein using nuclear magnetic resonance spectroscopy, adding a drug mimetic in order to learn how the structure EmrE was designed and how it functioned as it was transportingâ??moving the drug from the inside of the cell ... Researchers Look at Averting Drug Resistance - Drug Discovery & Development More...	nmrlearner	Online News	0	02-02-2012 09:43 PM
3D Proteins: Getting the Big Picture - Drug Discovery & Development 3D Proteins: Getting the Big Picture - Drug Discovery & Development http://nt3.ggpht.com/news/tbn/k64MPYPXLU8xiM/6.jpg Drug Discovery & Development <img alt="" height="1" width="1" /> 3D Proteins: Getting the Big Picture Drug Discovery & Development For decades, with funding from the National Science Foundation (NSF), Hinton has used nuclear magnetic resonance (NMR) to look at protein structure and function. But he wanted to find a way to educate and engage students about his discoveries. ... and more »	nmrlearner	Online News	0	05-10-2011 07:17 PM

« Previous Thread | Next Thread »

Posting Rules
You may not post new threads You may not post replies You may not post attachments You may not edit your posts BB code is On Smilies are On [IMG] code is On HTML code is On Trackbacks are Off Pingbacks are Off Refbacks are Off