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Proteinâ??protein interaction inhibitor tackles drug resistance - Nature.com
Proteinâ??protein interaction inhibitor tackles drug resistance - Nature.com
http://www.bionmr.com//t3.gstatic.co...1soEeLC0rNV-OM Nature.com <img alt="" height="1" width="1"> Proteinâ??protein interaction inhibitor tackles drug resistance Nature.com NMR spectroscopy was then used to determine the mechanism of action of the most potent compound, termed iKIX1. The high-resolution structure showed that iKIX1 binds to the three-helix hydrophobic groove of the KIX domain of Gal11A, engaging the same ... Read here |
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