A New Factor In Protein Folding Seeking Alpha
That's definitely not one of the the bonding modes that anyone would think of first, but the paper demonstrates actual detection of (very, very small) coupling constants in 2D NMR (HMQC) spectra that are due to through-space interactions of (say) the ...
Exploring Folding Cooperativity of a Repeat Protein Folding by 2D-NMR Detected Pressure Perturbation
Exploring Folding Cooperativity of a Repeat Protein Folding by 2D-NMR Detected Pressure Perturbation
Publication date: 16 February 2016
Source:Biophysical Journal, Volume 110, Issue 3, Supplement 1</br>
Author(s): Martin J. Fossat, Angel Garcia, Doug Barrick, Christian Roumestand, Catherine A. Royer</br>
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02-17-2016 07:50 PM
[NMR paper] Elucidating the folding problem of alpha-helices: local motifs, long-range electrosta
Elucidating the folding problem of alpha-helices: local motifs, long-range electrostatics, ionic-strength dependence and prediction of NMR parameters.
Related Articles Elucidating the folding problem of alpha-helices: local motifs, long-range electrostatics, ionic-strength dependence and prediction of NMR parameters.
J Mol Biol. 1998 Nov 20;284(1):173-91
Authors: Lacroix E, Viguera AR, Serrano L
The information about the conformational behavior of monomeric helical peptides in solution, as well as the alpha-helix stability in proteins, has...
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[NMR paper] Structure-based minimization of transforming growth factor-alpha (TGF-alpha) through
Structure-based minimization of transforming growth factor-alpha (TGF-alpha) through NMR analysis of the receptor-bound ligand. Design, solution structure, and activity of TGF-alpha 8-50.
Related Articles Structure-based minimization of transforming growth factor-alpha (TGF-alpha) through NMR analysis of the receptor-bound ligand. Design, solution structure, and activity of TGF-alpha 8-50.
J Biol Chem. 1998 Oct 16;273(42):27357-63
Authors: McInnes C, Wang J, Al Moustafa AE, Yansouni C, O'Connor-McCourt M, Sykes BD
The investigation of a...
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[NMR paper] NMR study of the transforming growth factor-alpha (TGF-alpha)-epidermal growth factor
NMR study of the transforming growth factor-alpha (TGF-alpha)-epidermal growth factor receptor complex. Visualization of human TGF-alpha binding determinants through nuclear Overhauser enhancement analysis.
http://www.ncbi.nlm.nih.gov/corehtml/query/egifs/http:--highwire.stanford.edu-icons-externalservices-pubmed-standard-jbc_full_free.gif Related Articles NMR study of the transforming growth factor-alpha (TGF-alpha)-epidermal growth factor receptor complex. Visualization of human TGF-alpha binding determinants through nuclear Overhauser enhancement analysis.
J Biol...
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[NMR paper] Solution structure of human type-alpha transforming growth factor determined by heter
Solution structure of human type-alpha transforming growth factor determined by heteronuclear NMR spectroscopy and refined by energy minimization with restraints.
Related Articles Solution structure of human type-alpha transforming growth factor determined by heteronuclear NMR spectroscopy and refined by energy minimization with restraints.
Biochemistry. 1993 Jul 27;32(29):7334-53
Authors: Moy FJ, Li YC, Rauenbuehler P, Winkler ME, Scheraga HA, Montelione GT
Human type-alpha transforming growth factor (hTGF alpha) is a small mitogenic protein...
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[NMR paper] NMR restraint analysis of transforming growth factor alpha: a key component for NMR s
NMR restraint analysis of transforming growth factor alpha: a key component for NMR structure refinement.
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Proteins. 1992 Aug;13(4):306-26
Authors: Brown FK, Hempel JC, Jeffs PW
Structures of the protein, transforming growth factor alpha (TGF-alpha), have been derived from NMR data using distance geometry and subsequent energy refinement. Analysis of the sequential NOE distance bounds using a template algorithm provides a...
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08-21-2010 11:45 PM
[NMR paper] Solution structures of human transforming growth factor alpha derived from 1H NMR dat
Solution structures of human transforming growth factor alpha derived from 1H NMR data.
Related Articles Solution structures of human transforming growth factor alpha derived from 1H NMR data.
Biochemistry. 1990 Aug 28;29(34):7805-13
Authors: Kline TP, Brown FK, Brown SC, Jeffs PW, Kopple KD, Mueller L
The 600-MHz 1H NMR spectrum of the des-Val-Val mutant of human transforming growth factor alpha (TGF-alpha) was reassigned at pH = 6.3. The conformation space of des-Val-Val TGF-alpha was explored by distance geometry embedding followed by...
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08-21-2010 11:04 PM
seeking expertise
Hello all,
I seek your expertise on a topic. I have a compound that I performed a 1H NMR temperature variation study on and there is one proton signal which moves upfield as I increase in temperature. All of the other signals remained the same. It's not like a case where the signal is coalescing (I know I demolished the spelling here) the signal just wandered upfield by about 0.8 ppm at and increase of 120 K in DMSO. Any ideas on this would be greatly appreciated!
Thanks!
Steve
A New Factor In Protein Folding - Seeking Alpha
Linear Mode
