Cell contents may be key to controlling toxicity of Huntington's protein - R & D Magazine

		BioNMR > NMR community > Online News
Cell contents may be key to controlling toxicity of Huntington's protein - R & D Magazine

Webservers

NMR processing:

MDD

NMR assignment:

Backbone:

Side-chains:

NOEs:

Structure from NMR restraints:

Ab initio:

Fragment-based:

Rosetta-NMR (Robetta)

Template-based:

GeNMR

I-TASSER

Refinement:

Amber

Structure from chemical shifts:

Fragment-based:

Homology-based:

Torsion angles from chemical shifts:

Preditor

TALOS

Promega- Proline

Secondary structure from chemical shifts:

CSI (via RCI server)

TALOS

MICS caps, β-turns

d2D

PECAN

Flexibility from chemical shifts:

RCI

Interactions from chemical shifts:

HADDOCK

Chemical shifts re-referencing:

NMR model quality:

NOEs, other restraints:

Chemical shifts:

RDCs:

Pseudocontact shifts:

Protein geomtery:

SAVES2 or SAVES4

Quality Control Check

NMR spectrum prediction:

FANDAS

MestReS

V-NMR

Flexibility from structure:

Backbone S2

Methyl S2

B-factor

Molecular dynamics:

Gromacs

Amber

Antechamber

Chemical shifts prediction:

From structure:

Shiftx2

Sparta+

Camshift

CH3shift- Methyl

ArShift- Aromatic

ShiftS

Proshift

PPM

CheShift-2- Cα

From sequence:

Shifty

Camcoil

Poulsen_rc_CS

Disordered proteins:

MAXOCC

Format conversion & validation:

CCPN

From NMR-STAR 3.1

Validate NMR-STAR 3.1

NMR sample preparation:

Protein disorder:

DisMeta

Protein solubility:

Isotope labeling:

Solid-state NMR:

View First Unread

Thread Tools

Search this Thread

Rate Thread

Display Modes

06-13-2012, 11:34 AM

nmrlearner

Senior Member

Join Date: Jan 2005

Posts: 23,178

Points: 193,617, Level: 100

Level up: 0%, 0 Points needed

Activity: 50.7%

Last Achievements

Award-Showcase

NMR Credits: 0

NMR Points: 193,617

Downloads: 0

Uploads: 0

Cell contents may be key to controlling toxicity of Huntington's protein - R & D Magazine

Cell contents may be key to controlling toxicity of Huntington's protein - R & D Magazine

Cell contents may be key to controlling toxicity of Huntington's protein
R & D Magazine
... suggests that the toxic effects of the huntingtin protein on cells may not be driven ... of a new 0.75-mm solid state nuclear magnetic resonance (NMR) probe.

Read here

Did you find this post helpful?

Similar Threads
Thread	Thread Starter	Forum	Replies	Last Post
Researchers develop way to strengthen proteins with polymers - R & D Magazine Researchers develop way to strengthen proteins with polymers - R & D Magazine http://www.bionmr.com//nt1.ggpht.com/news/tbn/1e8ZLQCvJy_rwM/6.jpg Azom.com <img alt="" height="1" width="1" /> Researchers develop way to strengthen proteins with polymers R & D Magazine Proteins are widely used as drugsâ??insulin for diabetics is the best known ... next week of a new 0.75-mm solid state nuclear magnetic resonance (NMR) probe. Polymers Can be Used to Stabilize ProteinsAzom.com	nmrlearner	Online News	0	06-13-2012 11:34 AM
Scientists Work Together to Achieve Milestone Against Deadly Diseases - Lab Manager Magazine <img alt="" height="1" width="1" /> Scientists Work Together to Achieve Milestone Against Deadly Diseases Lab Manager Magazine Researchers in both centers use X-ray crystallography and nuclear magnetic resonance to examine the atomic details of proteins from more than 40 human pathogens, including those responsible for the plague, anthrax, salmonellosis, cholera, ... and more » Scientists Work Together to Achieve Milestone Against Deadly Diseases - Lab Manager Magazine More...	nmrlearner	Online News	0	06-07-2012 06:58 AM
A New Tool to Reveal Structure of Proteins - Lab Manager Magazine A New Tool to Reveal Structure of Proteins - Lab Manager Magazine <img alt="" height="1" width="1" /> A New Tool to Reveal Structure of Proteins Lab Manager Magazine For roughly a decade, a technique called solid state nuclear magnetic resonance (NMR) spectroscopy has allowed researchers to detect the arrangements of atoms in proteins that defy study by traditional laboratory tools such as X-ray crystallography. and more » Read here	nmrlearner	Online News	0	03-20-2012 10:52 PM
$1.2M for Biomed Research - Lab Manager Magazine <img alt="" height="1" width="1" /> $1.2M for Biomed Research Lab Manager Magazine NIH also awarded UGA a $363700 grant for a new electronics console for the 800 MHz nuclear magnetic resonance spectrometer housed in the Fred C. Davison Life Sciences Complex. The more reliable console will further research in protein chemistry, ... $1.2M for Biomed Research - Lab Manager Magazine More...	nmrlearner	Online News	0	10-03-2011 08:40 PM
Study of acute biochemical effects of thallium toxicity in mouse urine by NMR spectroscopy. Study of acute biochemical effects of thallium toxicity in mouse urine by NMR spectroscopy. Study of acute biochemical effects of thallium toxicity in mouse urine by NMR spectroscopy. J Appl Toxicol. 2011 Jan 7; Authors: Tyagi R, Rana P, Khan AR, Bhatnagar D, Devi MM, Chaturvedi S, Tripathi RP, Khushu S Thallium (Tl) is a toxic heavy metal and its exposure to the human body causes physiological and biochemical changes due to its interference with potassium-dependent biological reactions. A high-resolution (1) H NMR spectroscopy based metabonomic...	nmrlearner	Journal club	0	01-11-2011 11:27 PM
[NMR paper] Cell-free protein synthesis in an autoinduction system for NMR studies of protein-protein interactions. Cell-free protein synthesis in an autoinduction system for NMR studies of protein-protein interactions. Related Articles Cell-free protein synthesis in an autoinduction system for NMR studies of protein-protein interactions. J Biomol NMR. 2005 Jul;32(3):235-41 Authors: Ozawa K, Jergic S, Crowther JA, Thompson PR, Wijffels G, Otting G, Dixon NA Cell-free protein synthesis systems provide facile access to proteins in a nascent state that enables formation of soluble, native protein-protein complexes even if one of the protein components is prone...	nmrlearner	Journal club	0	12-01-2010 06:56 PM
[NMR paper] Controlling residual dipolar couplings in high-resolution NMR of proteins by strain i Controlling residual dipolar couplings in high-resolution NMR of proteins by strain induced alignment in a gel. Related Articles Controlling residual dipolar couplings in high-resolution NMR of proteins by strain induced alignment in a gel. J Biomol NMR. 2001 Oct;21(2):141-51 Authors: Ishii Y, Markus MA, Tycko R Water-soluble biological macromolecules can be weakly aligned by dissolution in a strained, hydrated gel such as cross-linked polyacrylamide, an effect termed 'strain-induced alignment in a gel' (SAG). SAG induces nonzero nuclear...	nmrlearner	Journal club	0	11-19-2010 08:44 PM
[NMR paper] 1H NMR-based absolute quantitation of human lipoproteins and their lipid contents dir 1H NMR-based absolute quantitation of human lipoproteins and their lipid contents directly from plasma. Related Articles 1H NMR-based absolute quantitation of human lipoproteins and their lipid contents directly from plasma. J Lipid Res. 1994 Dec;35(12):2292-304 Authors: Ala-Korpela M, Korhonen A, Keisala J, HÃ¶rkkÃ¶ S, Korpi P, Ingman LP, Jokisaari J, Savolainen MJ, KesÃ¤niemi YA A new method is presented for absolute quantitation of lipid and protein contents of human lipoproteins directly from plasma. The method enables complete lipoprotein...	nmrlearner	Journal club	0	08-22-2010 03:29 AM

« Previous Thread | Next Thread »

Posting Rules
You may not post new threads You may not post replies You may not post attachments You may not edit your posts BB code is On Smilies are On [IMG] code is On HTML code is On Trackbacks are Off Pingbacks are Off Refbacks are Off