[NMR paper] Detection of Lung Cancer via Blood Plasma and (1)H-NMR Metabolomics: Validation by a Semi-Targeted and Quantitative Approach Using a Protein-Binding Competitor
Detection of Lung Cancer via Blood Plasma and (1)H-NMR Metabolomics: Validation by a Semi-Targeted and Quantitative Approach Using a Protein-Binding Competitor
Metabolite profiling of blood plasma, by proton nuclear magnetic resonance (¹H-NMR) spectroscopy, offers great potential for early cancer diagnosis and unraveling disruptions in cancer metabolism. Despite the essential attempts to standardize pre-analytical and external conditions, such as pH or temperature, the donor-intrinsic plasma protein concentration is highly overlooked. However, this is of utmost importance, since several...
nmrlearner
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08-27-2021 03:49 PM
[NMR paper] Insights into the Binding of Cyclic RGD Peptidomimetics to ?5?1 Integrin by using Live-Cell NMR And Computational Studies.
Insights into the Binding of Cyclic RGD Peptidomimetics to ?5?1 Integrin by using Live-Cell NMR And Computational Studies.
Related Articles Insights into the Binding of Cyclic RGD Peptidomimetics to ?5?1 Integrin by using Live-Cell NMR And Computational Studies.
ChemistryOpen. 2017 Feb;6(1):128-136
Authors: Guzzetti I, Civera M, Vasile F, Arosio D, Tringali C, Piarulli U, Gennari C, Pignataro L, Belvisi L, Potenza D
Abstract
The interaction of a small library of cyclic DKP-RGD peptidomimetics with ?5?1 integrin has been...
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02-09-2017 12:19 PM
Elucidation of Lipid Binding Sites on Lung SurfactantProtein A Using X-ray Crystallography, Mutagenesis, and MolecularDynamics Simulations
Elucidation of Lipid Binding Sites on Lung SurfactantProtein A Using X-ray Crystallography, Mutagenesis, and MolecularDynamics Simulations
http://pubs.acs.org/appl/literatum/publisher/achs/journals/content/bichaw/0/bichaw.ahead-of-print/acs.biochem.6b00048/20160620/images/medium/bi-2016-00048k_0010.gif
Biochemistry
DOI: 10.1021/acs.biochem.6b00048
http://feeds.feedburner.com/~ff/acs/bichaw?d=yIl2AUoC8zA
http://feeds.feedburner.com/~r/acs/bichaw/~4/Nn6Ip0uz_qA
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06-22-2016 06:54 AM
IISc's killer discovery to fight multiple drug resistant TB bacteria - Bangalore Mirror
<img alt="" height="1" width="1" />
IISc's killer discovery to fight multiple drug resistant TB bacteria
Bangalore Mirror
While the Physics department helped with crystallography of proteins and computational biology, the department of Biophysics helped with nuclear magnetic resonance (NMR) spectroscopy which found that the SD1 molecule binds to the protein. Biology ...
IISc's killer discovery to fight multiple drug resistant TB bacteria - Bangalore Mirror
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nmrlearner
Online News
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06-15-2014 04:45 AM
[Question from NMRWiki Q&A forum] Avance III 400 NMR lift unresponsive... emergency air lift activiated
Avance III 400 NMR lift unresponsive... emergency air lift activiated
Hi, I am unable to activate our lift on our avance III 400 NMR from BruKer The message is emergency air lift activated. Both the inject and eject commands give this error. And I am unable to hear of air flow through the lift or any other mechanism when a lift is attempted. We could still lock on and shim to the chloroform peak. I've gone through a couple of trouble shooting pathways but so far I'm unsuccessful and getting our lift to work and shutting off the emergency air flow.
Does any one have any suggestions? ...
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News from other NMR forums
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05-25-2013 12:05 PM
[NMR paper] The zinc-binding fragment of HypA from Helicobacter pylori: a tempting site also for nickel ions.
The zinc-binding fragment of HypA from Helicobacter pylori: a tempting site also for nickel ions.
http://www.ncbi.nlm.nih.gov/corehtml/query/egifs/http:--www.rsc.org-images-entities-char_z_RSClogo.gif Related Articles The zinc-binding fragment of HypA from Helicobacter pylori: a tempting site also for nickel ions.
Dalton Trans. 2013 Jan 21;
Authors: Rowinska-Zyrek M, Potocki S, Witkowska D, Valensin D, Kozlowski H
Abstract
HypA, a nickel accessory protein from H. pylori, binds a zinc ion in it's structural site, a loop with two conserved...
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02-03-2013 10:19 AM
[NMR paper] What NMR can tell us about where lung surfactant proteins live.
What NMR can tell us about where lung surfactant proteins live.
Related Articles What NMR can tell us about where lung surfactant proteins live.
Biochem Soc Trans. 1997 Aug;25(3):1103-7
Authors: Morrow MR, Taneva S, Dico AS, Hancock J, Keough KM
2H-NMR is beginning to provide some insights into the way in which the hydrophobic surfactant proteins SP-B and SP-C interact with phospholipid bilayers in multilamellar structures. Both proteins have a significant effect on slow bilayer motions. In many ways, the effect of SP-C on the surrounding...
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08-22-2010 05:08 PM
[NMR paper] Characterization of the solution properties of Pichia farinosa killer toxin using PGS
Characterization of the solution properties of Pichia farinosa killer toxin using PGSE NMR diffusion measurements.
Characterization of the solution properties of Pichia farinosa killer toxin using PGSE NMR diffusion measurements.
J Biomol NMR. 1999 Feb;13(2):113-7
Authors: Price WS, Tsuchiya F, Suzuki C, Arata Y
The solution behaviour with respect to pH and NaCl concentration of the tertiary structure and propensity for aggregation of salt- mediated killer toxin (SMKT) from Pichia farinosa was examined using pulsed-gradient spin-echo NMR...
Binding with a 'messy' protein: how nickel becomes the lung killer - Emergency Live International
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