When to label peptides and proteins and when not?
 

When to label peptides and proteins and when not?

When pursuing an NMR structure project - at what size of oligopeptide you would decide to label it with:

• 15N
• 13C
• both

Have you worked with a non-labeled oligopeptide where you thought later "I wish I've labeled it" - how many residues did it have?

Thanks.



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