Barskiy, D.A., et al., In Situ and Ex Situ Low-Field NMR Spectroscopy and MRI Endowed by SABRE Hyperpolarization. ChemPhysChem, 2014. 15(18): p. 4100-7.
By using 5.75 and 47.5 mT nuclear magnetic resonance (NMR) spectroscopy, up to 10(5) -fold sensitivity enhancement through signal amplification by reversible exchange (SABRE) was enabled, and subsecond temporal resolution was used to monitor an exchange reaction that resulted in the buildup and decay of hyperpolarized species after parahydrogen bubbling. We demonstrated the high-resolution low-field proton magnetic resonance imaging (MRI) of pyridine in a 47.5 mT magnetic field endowed by SABRE. Molecular imaging (i.e. imaging of dilute hyperpolarized substances rather than the bulk medium) was conducted in two regimes: in situ real-time MRI of the reaction mixture (in which pyridine was hyperpolarized), and ex situ MRI (in which hyperpolarization decays) of the liquid hyperpolarized product. Low-field (milli-Tesla range, e.g. 5.75 and 47.5 mT used in this study) parahydrogen-enhanced NMR and MRI, which are free from the limitations of high-field magnetic resonance (including susceptibility-induced gradients of the static magnetic field at phase interfaces), potentially enables new imaging applications as well as differentiation of hyperpolarized chemical species on demand by exploiting spin manipulations with static and alternating magnetic fields.
Ab InitioStructure Search and in Situ 7Li NMR Studies of DischargeProducts in the Li–S Battery System
Ab InitioStructure Search and in Situ 7Li NMR Studies of DischargeProducts in the Li–S Battery System
Kimberly A. See, Michal Leskes, John M. Griffin, Sylvia Britto, Peter D. Matthews, Alexandra Emly, Anton Van der Ven, Dominic S. Wright, Andrew J. Morris, Clare P. Grey and Ram Seshadri
http://pubs.acs.org/appl/literatum/publisher/achs/journals/content/jacsat/0/jacsat.ahead-of-print/ja508982p/20141110/images/medium/ja-2014-08982p_0009.gif
Journal of the American Chemical Society
DOI: 10.1021/ja508982p
http://feeds.feedburner.com/~ff/acs/jacsat?d=yIl2AUoC8zA...
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11-10-2014 10:59 PM
Structural Characterization of Micro- and Mesoporous Carbon Materials Using In Situ High Pressure129Xe NMR Spectroscopy
From The DNP-NMR Blog:
Structural Characterization of Micro- and Mesoporous Carbon Materials Using In Situ High Pressure129Xe NMR Spectroscopy
Oschatz, M., et al., Structural Characterization of Micro- and Mesoporous Carbon Materials Using In Situ High Pressure129Xe NMR Spectroscopy. Chemistry of Materials, 2014. 26(10): p. 3280-3288.
http://dx.doi.org/10.1021/cm501102y
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05-31-2014 01:47 AM
Toward nanomolar detection by NMR through SABRE hyperpolarization
From The DNP-NMR Blog:
Toward nanomolar detection by NMR through SABRE hyperpolarization
Eshuis, N., et al., Toward nanomolar detection by NMR through SABRE hyperpolarization. J Am Chem Soc, 2014. 136(7): p. 2695-8.
http://www.ncbi.nlm.nih.gov/pubmed/24475903
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05-09-2014 07:01 PM
TowardNanomolar Detection by NMR Through SABRE Hyperpolarization
TowardNanomolar Detection by NMR Through SABRE Hyperpolarization
Nan Eshuis, Niels Hermkens, Bram J. A. van Weerdenburg, Martin C. Feiters, Floris P. J. T. Rutjes, Sybren S. Wijmenga and Marco Tessari
http://pubs.acs.org/appl/literatum/publisher/achs/journals/content/jacsat/0/jacsat.ahead-of-print/ja412994k/aop/images/medium/ja-2013-12994k_0006.gif
Journal of the American Chemical Society
DOI: 10.1021/ja412994k
http://feeds.feedburner.com/~ff/acs/jacsat?d=yIl2AUoC8zA
http://feeds.feedburner.com/~r/acs/jacsat/~4/CRRo27dOPlc
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[NMR paper] Real-time kinetics of high-mobility group box 1 oxidation in extracellular fluids studied by in situ protein NMR spectroscopy.
Real-time kinetics of high-mobility group box 1 oxidation in extracellular fluids studied by in situ protein NMR spectroscopy.
Real-time kinetics of high-mobility group box 1 oxidation in extracellular fluids studied by in situ protein NMR spectroscopy.
J Biol Chem. 2013 Feb 27;
Authors: Zandarashvili L, Sahu D, Lee K, Lee YS, Singh P, Rajarathnam K, Iwahara J
Abstract
Some extracellular proteins are initially secreted in the reduced form via a non-canonical pathway bypassing the endoplasmic reticulum, and become oxidized in the...
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03-01-2013 09:57 PM
High-Pressure in Situ 129Xe NMR Spectroscopy and Computer Simulations of Breathing Transitions in the Metal–Organic Framework Ni2(2,6-ndc)2(dabco) (DUT-8(Ni))
High-Pressure in Situ 129Xe NMR Spectroscopy and Computer Simulations of Breathing Transitions in the Metal–Organic Framework Ni2(2,6-ndc)2(dabco) (DUT-8(Ni))
Herbert C. Hoffmann, Bassem Assfour, Fanny Epperlein, Nicole Klein, Silvia Paasch, Irena Senkovska, Stefan Kaskel, Gotthard Seifert and Eike Brunner
http://pubs.acs.org/appl/literatum/publisher/achs/journals/content/jacsat/0/jacsat.ahead-of-print/ja201951t/aop/images/medium/ja-2011-01951t_0001.gif
Journal of the American Chemical Society
DOI: 10.1021/ja201951t
http://feeds.feedburner.com/~ff/acs/jacsat?d=yIl2AUoC8zA...
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[NMR paper] 31P NMR saturation-transfer study of the in situ kinetics of the mitochondrial adenin
31P NMR saturation-transfer study of the in situ kinetics of the mitochondrial adenine nucleotide translocase.
Related Articles 31P NMR saturation-transfer study of the in situ kinetics of the mitochondrial adenine nucleotide translocase.
Biochemistry. 1991 Aug 27;30(34):8351-7
Authors: Masiakos PT, Williams GD, Berkich DA, Smith MB, LaNoue KF
The exchange of intramitochondrial ATP (ATP(in)) for extramitochondrial ATP (ATP(out)) was measured by using 31P NMR spectroscopy over a range of temperatures in isolated rat liver mitochondria oxidizing...
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08-21-2010 11:12 PM
[NMR paper] 31P NMR saturation-transfer study of the in situ kinetics of the mitochondrial adenin
31P NMR saturation-transfer study of the in situ kinetics of the mitochondrial adenine nucleotide translocase.
Related Articles 31P NMR saturation-transfer study of the in situ kinetics of the mitochondrial adenine nucleotide translocase.
Biochemistry. 1991 Aug 27;30(34):8351-7
Authors: Masiakos PT, Williams GD, Berkich DA, Smith MB, LaNoue KF
The exchange of intramitochondrial ATP (ATP(in)) for extramitochondrial ATP (ATP(out)) was measured by using 31P NMR spectroscopy over a range of temperatures in isolated rat liver mitochondria oxidizing...
In Situ and Ex Situ Low-Field NMR Spectroscopy and MRI Endowed by SABRE Hyperpolarization
Linear Mode
