Hata, R., et al., Design of a hyperpolarized 15N NMR probe that induces a large chemical-shift change upon binding of calcium ions. Chemical Communications, 2015. 51(61): p. 12290-12292.
Ca2+ is a fundamental metal ion for physiological functioning. Therefore, molecular probes for Ca2+ analysis are required. Recently, a hyperpolarized NMR probe has emerged as a promising tool. Here, we report a new design of a hyperpolarized NMR probe for Ca2+, which showed a large chemical shift change upon binding to Ca2+ and was applied for Ca2+ sensing in a hyperpolarized state.
Hyperpolarized cesium ions doped in a glass material
From The DNP-NMR Blog:
Hyperpolarized cesium ions doped in a glass material
Ishikawa, K., Hyperpolarized cesium ions doped in a glass material. J Magn Reson, 2014. 249C(0): p. 94-99.
http://www.ncbi.nlm.nih.gov/pubmed/25462952
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12-12-2014 11:39 PM
[NMR paper] EZ-ASSIGN, a program for exhaustive NMR chemical shift assignments of large proteins from complete or incomplete triple-resonance data.
EZ-ASSIGN, a program for exhaustive NMR chemical shift assignments of large proteins from complete or incomplete triple-resonance data.
http://www.bionmr.com//www.ncbi.nlm.nih.gov/corehtml/query/egifs/http:--production.springer.de-OnlineResources-Logos-springerlink.gif Related Articles EZ-ASSIGN, a program for exhaustive NMR chemical shift assignments of large proteins from complete or incomplete triple-resonance data.
J Biomol NMR. 2013 Sep 11;
Authors: Zuiderweg ER, Bagai I, Rossi P, Bertelsen EB
Abstract
For several of the proteins...
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09-12-2013 11:02 PM
[NMR paper] PUMA binding induces partial unfolding within BCL-xL to disrupt p53 binding and promote apoptosis.
PUMA binding induces partial unfolding within BCL-xL to disrupt p53 binding and promote apoptosis.
http://www.ncbi.nlm.nih.gov/corehtml/query/egifs/http:--www.nature.com-images-npg_logo.gif Related Articles PUMA binding induces partial unfolding within BCL-xL to disrupt p53 binding and promote apoptosis.
Nat Chem Biol. 2013 Jan 20;
Authors: Follis AV, Chipuk JE, Fisher JC, Yun MK, Grace CR, Nourse A, Baran K, Ou L, Min L, White SW, Green DR, Kriwacki RW
Abstract
Following DNA damage, nuclear p53 induces the expression of PUMA, a BH3-only...
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02-03-2013 10:19 AM
1H NMR Chemical Shift Calculations as a Probe of Supramolecular Host–Guest Geometry
1H NMR Chemical Shift Calculations as a Probe of Supramolecular Host–Guest Geometry
Jeffrey S. Mugridge, Robert G. Bergman and Kenneth N. Raymond
http://pubs.acs.org/appl/literatum/publisher/achs/journals/content/jacsat/0/jacsat.ahead-of-print/ja202254x/aop/images/medium/ja-2011-02254x_0010.gif
Journal of the American Chemical Society
DOI: 10.1021/ja202254x
http://feeds.feedburner.com/~ff/acs/jacsat?d=yIl2AUoC8zA
http://feeds.feedburner.com/~r/acs/jacsat/~4/wR-1b5WtJhc
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06-30-2011 05:01 AM
Exploring NMR ensembles of calcium binding proteins: perspectives to design inhibitors of protein-protein interactions.
Exploring NMR ensembles of calcium binding proteins: perspectives to design inhibitors of protein-protein interactions.
Exploring NMR ensembles of calcium binding proteins: perspectives to design inhibitors of protein-protein interactions.
BMC Struct Biol. 2011 May 12;11(1):24
Authors: Isvoran A, Badel A, Craescu CT, Miron S, Miteva MA
ABSTRACT: BACKGROUND: Disrupting protein-protein interactions by small organic molecules is nowadays a promising strategy employed to block protein targets involved in different pathologies. However, structural...
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05-17-2011 06:21 PM
Exploring NMR ensembles of calcium binding proteins: perspectives to design ... - 7thSpace Interactive (press release)
Exploring NMR ensembles of calcium binding proteins: perspectives to design ... - 7thSpace Interactive (press release)
<img alt="" height="1" width="1" />
Exploring NMR ensembles of calcium binding proteins: perspectives to design ...
7thSpace Interactive (press release)
We employed several scoring methods in order to find the best protein conformations. Our results show that docking on NMR structures of calmodulin and centrin can be very helpful to take into account conformational changes occurring at protein-protein ...
Read here
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05-13-2011 07:41 AM
[NMR paper] Biomolecular NMR using a microcoil NMR probe--new technique for the chemical shift as
Biomolecular NMR using a microcoil NMR probe--new technique for the chemical shift assignment of aromatic side chains in proteins.
Related Articles Biomolecular NMR using a microcoil NMR probe--new technique for the chemical shift assignment of aromatic side chains in proteins.
J Am Chem Soc. 2004 May 12;126(18):5873-8
Authors: Peti W, Norcross J, Eldridge G, O'Neil-Johnson M
A specially designed microcoil probe for use in biomolecular NMR spectroscopy is presented. The microcoil probe shows a mass-based sensitivity increase of a minimal...
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11-24-2010 09:51 PM
[NMR paper] Chemical shift as a probe of molecular interfaces: NMR studies of DNA binding by the
Chemical shift as a probe of molecular interfaces: NMR studies of DNA binding by the three amino-terminal zinc finger domains from transcription factor IIIA.
Related Articles Chemical shift as a probe of molecular interfaces: NMR studies of DNA binding by the three amino-terminal zinc finger domains from transcription factor IIIA.
J Biomol NMR. 1998 Jul;12(1):51-71
Authors: Foster MP, Wuttke DS, Clemens KR, Jahnke W, Radhakrishnan I, Tennant L, Reymond M, Chung J, Wright PE
We report the NMR resonance assignments for a macromolecular...
Design of a hyperpolarized 15N NMR probe that induces a large chemical-shift change upon binding of calcium ions
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