Zinc-binding structure of a catalytic amyloid from solid-state NMR [Biophysics and Computational Biology]
 

Zinc-binding structure of a catalytic amyloid from solid-state NMR [Biophysics and Computational Biology]

Myungwoon Lee, Tuo Wang, Olga V. Makhlynets, Yibing Wu, Nicholas F. Polizzi, Haifan Wu, Pallavi M. Gosavi, Jan Stohr, Ivan V. Korendovych, William F. DeGrado, Mei Hong...
Date: 2017-06-13

Throughout biology, amyloids are key structures in both functional proteins and the end product of pathologic protein misfolding. Amyloids might also represent an early precursor in the evolution of life because of their small molecular size and their ability to self-purify and catalyze chemical reactions. They also provide attractive backbones... Read More


PNAS:
Number: 24
Volume: 114