What NMR can tell us about where lung surfactant proteins live.
 

What NMR can tell us about where lung surfactant proteins live.

Related Articles What NMR can tell us about where lung surfactant proteins live.

Biochem Soc Trans. 1997 Aug;25(3):1103-7

Authors: Morrow MR, Taneva S, Dico AS, Hancock J, Keough KM

2H-NMR is beginning to provide some insights into the way in which the hydrophobic surfactant proteins SP-B and SP-C interact with phospholipid bilayers in multilamellar structures. Both proteins have a significant effect on slow bilayer motions. In many ways, the effect of SP-C on the surrounding bilayer is similar to that of other transmembrane proteins. Ca2+ appears to modify the way in which SP-C perturbs the bilayers containing DPPG. The effect of SP-B on bilayers differs, in subtle ways, from that expected for a transmembrane protein.

PMID: 9388607 [PubMed - indexed for MEDLINE]



Source: PubMed