Lipoprotein profile in PCOS may lead to insight on CV risk - Healio
Lipoprotein profile in PCOS may lead to insight on CV risk - Healio
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Lipoprotein profile in PCOS may lead to insight on CV risk
Healio
Nuclear magnetic resonance (NMR) spectroscopy was used to measure LDL particle size and number. Compared with controls, participants with PCOS had higher LDL particle numbers (P = .032). High-sensitivity C-reactive protein (P = .006) and waist-to-hip ...
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09-22-2015 06:40 PM
Interactionsof Bacterial Cell Division Protein FtsZwith C8-Substituted Guanine Nucleotide Inhibitors. A Combined NMR,Biochemical and Molecular Modeling Perspective
Interactionsof Bacterial Cell Division Protein FtsZwith C8-Substituted Guanine Nucleotide Inhibitors. A Combined NMR,Biochemical and Molecular Modeling Perspective
Filipa Marcelo, Sonia Huecas, Laura B. Ruiz-A?vila, F. Javier Can?ada, Almudena Perona, Ana Poveda, Sonsoles Marti?n-Santamari?a, Antonio Morreale, Jesu?s Jime?nez-Barbero and Jose? M. Andreu
http://pubs.acs.org/appl/literatum/publisher/achs/journals/content/jacsat/0/jacsat.ahead-of-print/ja405515r/aop/images/medium/ja-2013-05515r_0010.gif
Journal of the American Chemical Society
DOI: 10.1021/ja405515r...
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10-24-2013 08:45 PM
[NMR paper] Backbone NMR assignments of a topologically knotted protein in urea-denatured state.
Backbone NMR assignments of a topologically knotted protein in urea-denatured state.
Related Articles Backbone NMR assignments of a topologically knotted protein in urea-denatured state.
Biomol NMR Assign. 2013 Jul 14;
Authors: Hsieh SJ, Mallam AL, Jackson SE, Hsu ST
Abstract
YibK is a tRNA methyltransferase from Haemophilus influenzae, which forms a stable homodimer in solution and contains a deep trefoil 31 knot encompassing the C-terminal helix that threads through a long loop. It has been a model system for investigating knotted...
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07-16-2013 09:04 PM
[NMR paper] Backbone NMR assignments of a topologically knotted protein in urea-denatured state.
Backbone NMR assignments of a topologically knotted protein in urea-denatured state.
Related Articles Backbone NMR assignments of a topologically knotted protein in urea-denatured state.
Biomol NMR Assign. 2013 Jul 3;
Authors: Hsieh SJ, Mallam AL, Jackson SE, Hsu ST
Abstract
YbeA is a 3-methylpseudoridine methyltransferase from Escherichia coli that forms a stable homodimer in solution. It is one of the deeply trefoil 31 knotted proteins, of which the knot encompasses the C-terminal helix that threads through a long loop. Recent...
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07-05-2013 08:03 AM
Thermodynamic and NMR analysis of inhibitor binding to dihydrofolate reductase.
Thermodynamic and NMR analysis of inhibitor binding to dihydrofolate reductase.
Thermodynamic and NMR analysis of inhibitor binding to dihydrofolate reductase.
Bioorg Med Chem. 2010 Dec 15;18(24):8485-92
Authors: Batruch I, Javasky E, Brown ED, Organ MG, Johnson PE
Isothermal titration calorimetry (ITC) was used to determine the thermodynamic driving force for inhibitor binding to the enzyme dihydrofolate reductase (DHFR) from Escherichia coli. 1,4-Bis-{sulfanylmethyl}-3,6-dimethyl-benzene (1) binds DHFR:NADPH with a K(d) of 13±5 nM while the...
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03-09-2011 02:20 PM
[NMR paper] Thermodynamic interpretation of protein dynamics from NMR relaxation measurements.
Thermodynamic interpretation of protein dynamics from NMR relaxation measurements.
Related Articles Thermodynamic interpretation of protein dynamics from NMR relaxation measurements.
Protein Pept Lett. 2005 Apr;12(3):235-40
Authors: Spyracopoulos L
Protein dynamics and thermodynamics can be characterized through measurements of relaxation rates of side chain (2)H and (13)C, and backbone (15)N nuclei using NMR spectroscopy. The rates reflect protein motions on timescales from picoseconds to milliseconds. Backbone and methyl side chain NMR...
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11-25-2010 08:21 PM
[NMR paper] Thermodynamic insights into proteins from NMR spin relaxation studies.
Thermodynamic insights into proteins from NMR spin relaxation studies.
Related Articles Thermodynamic insights into proteins from NMR spin relaxation studies.
Curr Opin Struct Biol. 2001 Oct;11(5):555-9
Authors: Spyracopoulos L, Sykes BD
NMR spin relaxation measurements of picosecond to nanosecond timescale backbone and sidechain fluctuations of protein molecules, and subsequent entropic interpretation yield interesting, but sometimes counterintuitive, insights into proteins. The stabilities of proteins and protein interactions are achieved...
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11-19-2010 08:44 PM
[NMR paper] NMR determination of residual structure in a urea-denatured protein, the 434-represso
NMR determination of residual structure in a urea-denatured protein, the 434-repressor.
Related Articles NMR determination of residual structure in a urea-denatured protein, the 434-repressor.
Science. 1992 Sep 11;257(5076):1559-63
Authors: Neri D, Billeter M, Wider G, Wüthrich K
A nuclear magnetic resonance (NMR) structure determination is reported for the polypeptide chain of a globular protein in strongly denaturing solution. Nuclear Overhauser effect (NOE) measurements with a 7 molar urea solution of the amino-terminal 63-residue domain...
Volumetrically Derived Thermodynamic Profile of Interactionsof Urea with a Native Protein
Linear Mode
