Two-dimensional NMR studies and secondary structure of cobrotoxin in aqueous solution
 

Two-dimensional NMR studies and secondary structure of cobrotoxin in aqueous solution.

http://www.ncbi.nlm.nih.gov/corehtml...REE_120x27.gif Related Articles Two-dimensional NMR studies and secondary structure of cobrotoxin in aqueous solution.

Eur J Biochem. 1990 Nov 13;193(3):789-99

Authors: Yu C, Lee CS, Chuang LC, Shei YR, Wang CY

The 1H-NMR spectra of cobrotoxin, a neurotoxic protein isolated from Formosan cobra Naja naja atra, have been studied by two-dimensional NMR techniques. Of 62 amino acid residues in cobrotoxin, the complete assignments of 58 residues have been made. The resonances from several of the remaining residues have been identified but not yet specifically assigned. The secondary structure of an antiparallel triple- and double-stranded beta-sheet has also been determined by observing the NOE.

PMID: 2249693 [PubMed - indexed for MEDLINE]



Source: PubMed