Two-dimensional heteronuclear saturation transfer difference NMR reveals detailed int
 

Two-dimensional heteronuclear saturation transfer difference NMR reveals detailed integrin αvβ6 protein-peptide interactions.

Related Articles Two-dimensional heteronuclear saturation transfer difference NMR reveals detailed integrin αvβ6 protein-peptide interactions.

Chem Commun (Camb). 2010 Sep 13;

Authors: Wagstaff JL, Vallath S, Marshall JF, Williamson RA, Howard MJ

We report the first example of peptide-protein heteronuclear two-dimensional (2D) saturation transfer difference nuclear magnetic resonance (STD NMR). This method, resulting in dramatically reduced overlap, was applied to the interaction of the integrin αvβ6 with a known peptide ligand and highlights novel contact points between the substrate and target protein.

PMID: 20838674 [PubMed - as supplied by publisher]



Source: PubMed