[NMR paper] Gd(3+)-chelated lipid accelerates solid-state NMR spectroscopy of seven-transmembrane proteins.
Gd(3+)-chelated lipid accelerates solid-state NMR spectroscopy of seven-transmembrane proteins.
Related Articles Gd(3+)-chelated lipid accelerates solid-state NMR spectroscopy of seven-transmembrane proteins.
J Biomol NMR. 2017 May 30;:
Authors: Liu C, Liu J, Xu X, Xiang S, Wang S
Abstract
Solid-state NMR (SSNMR) is an attractive technique for studying large membrane proteins in membrane-mimetic environments. However, SSNMR experiments often suffer from low efficiency, due to the inherent low sensitivity and the long recycle...
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06-01-2017 03:02 PM
[NMR paper] Structural Elucidation of Transmembrane Transporter Protein Bilitranslocase: Conformational analysis of the second transmembrane region TM2 by molecular dynamics and NMR spectroscopy.
Structural Elucidation of Transmembrane Transporter Protein Bilitranslocase: Conformational analysis of the second transmembrane region TM2 by molecular dynamics and NMR spectroscopy.
Related Articles Structural Elucidation of Transmembrane Transporter Protein Bilitranslocase: Conformational analysis of the second transmembrane region TM2 by molecular dynamics and NMR spectroscopy.
Biochim Biophys Acta. 2013 Jun 14;
Authors: Choudhury AR, Perdih A, Zuperl S, Sikorska E, Solmajer T, Jurga S, Zhukov I, Novi? M
Abstract
Membrane proteins...
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06-19-2013 08:55 PM
Structural Elucidation of Transmembrane Transporter Protein Bilitranslocase: Conformational analysis of the second transmembrane region TM2 by molecular dynamics and NMR spectroscopy
Structural Elucidation of Transmembrane Transporter Protein Bilitranslocase: Conformational analysis of the second transmembrane region TM2 by molecular dynamics and NMR spectroscopy
Publication date: Available online 14 June 2013
Source:Biochimica et Biophysica Acta (BBA) - Biomembranes</br>
Author(s): Amrita Roy Choudhury , Andrej Perdih , Špela Župerl , Emilia Sikorska , Tom Solmajer , Stefan Jurga , Igor Zhukov , Marjana Novi?</br>
Membrane proteins represent about a third of the gene products in most organisms, as revealed by the genome sequencing...
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06-15-2013 08:18 AM
[NMR paper] First Solution Structures of Seven-Transmembrane Helical Proteins
From Mendeley Biomolecular NMR group:
First Solution Structures of Seven-Transmembrane Helical Proteins
Angewandte Chemie International Edition (2011). Pages: n/a-n/a. Oliver Zerbe et al.
Published using Mendeley: Academic software for researchers
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08-24-2012 08:01 PM
Measurement of protein unfolding/refolding kinetics and structural characterization of hidden intermediates by NMR relaxation dispersion [Biophysics and Computational Biology]
Measurement of protein unfolding/refolding kinetics and structural characterization of hidden intermediates by NMR relaxation dispersion
Meinhold, D. W., Wright, P. E....
Date: 2011-05-31
Detailed understanding of protein function and malfunction hinges on the ability to characterize transiently populated states and the transitions between them. Here, we use 15N, , and 13CO NMR R2 relaxation dispersion to investigate spontaneous unfolding and refolding events of native apomyoglobin. Above pH 5.0, dispersion is dominated by processes involving fluctuations of the F-helix region, which...
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05-31-2011 11:41 PM
Measurement of protein unfolding/refolding kinetics and structural characterization of hidden intermediates by NMR relaxation dispersion.
Measurement of protein unfolding/refolding kinetics and structural characterization of hidden intermediates by NMR relaxation dispersion.
Measurement of protein unfolding/refolding kinetics and structural characterization of hidden intermediates by NMR relaxation dispersion.
Proc Natl Acad Sci U S A. 2011 May 11;
Authors: Meinhold DW, Wright PE
Detailed understanding of protein function and malfunction hinges on the ability to characterize transiently populated states and the transitions between them. Here, we use (15)N, , and (13)CO NMR R(2)...
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05-13-2011 02:40 PM
Choosing membrane mimetics for NMR structural studies of transmembrane proteins.
Choosing membrane mimetics for NMR structural studies of transmembrane proteins.
Choosing membrane mimetics for NMR structural studies of transmembrane proteins.
Biochim Biophys Acta. 2011 Apr 5;
Authors: Warschawski DE, Arnold AA, Beaugrand M, Gravel A, Chartrand E, Marcotte I
The native environment of membrane proteins is complex and scientists have felt the need to simplify it to reduce the number of varying parameters. However, experimental problems can also arise from oversimplification which contributes to why membrane proteins are...
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04-12-2011 11:08 AM
[NMR analysis blog] Hexacyclinol - NMR spectra vs plain images
Hexacyclinol - NMR spectra vs plain images
I’m sure that many of you are aware of the infamous controversy over the total synthesis of Hexacyclinol . There are a plethora of arguments, from the purely synthetic chemical point of view to the spectroscopist perspective, which both put in doubt the veracity of aforementioned total synthesis. You can find, at the end of this post, a list of references that may be of interest on this subject. In this particular post, I would like to comment on several interesting aspects from an NMR standpoint.
In the original article’s “supporting...
Transmembrane Proteins: Amyloids Hidden in Plain Sight?
Linear Mode
