Structural Insights into the Dimeric Form of Bacillus subtilis RNase Y Using NMR and AlphaFold
 

Structural Insights into the Dimeric Form of Bacillus subtilis RNase Y Using NMR and AlphaFold

RNase Y is a crucial component of genetic translation, acting as the key enzyme initiating mRNA decay in many Gram-positive bacteria. The N-terminal domain of Bacillus subtilis RNase Y (Nter-BsRNaseY) is thought to interact with various protein partners within a degradosome complex. Bioinformatics and biophysical analysis have previously shown that Nter-BsRNaseY, which is in equilibrium between a monomeric and a dimeric form, displays an elongated fold with a high content of ?-helices. Using...

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