[NMR paper] Deciphering the Binding Interactions between Acinetobacter baumannii ACP and beta-ketoacyl ACP Synthase III to Improve Antibiotic Targeting Using NMR Spectroscopy
Deciphering the Binding Interactions between Acinetobacter baumannii ACP and beta-ketoacyl ACP Synthase III to Improve Antibiotic Targeting Using NMR Spectroscopy
Fatty acid synthesis is essential for bacterial viability. Thus, fatty acid synthases (FASs) represent effective targets for antibiotics. Nevertheless, multidrug-resistant bacteria, including the human opportunistic bacteria, Acinetobacter baumannii, are emerging threats. Meanwhile, the FAS pathway of A. baumannii is relatively unexplored. Considering that acyl carrier protein (ACP) has an important role in the delivery of fatty...
PSC's Bridges Helps Scientists Understand Monkey Protein that Confers Immunity to HIV - HPCwire
PSC's Bridges Helps Scientists Understand Monkey Protein that Confers Immunity to HIV - HPCwire
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HPCwire
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PSC's Bridges Helps Scientists Understand Monkey Protein that Confers Immunity to HIV
HPCwire
Angela Gronenborn of Pitt and Tatyana Polenova of Delaware used a lab technique called nuclear magnetic resonance (NMR) to study which parts of the virus's capsid protein, called CA, are affected when TRIM5α is present. NMR...
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11-25-2018 06:02 AM
[NMR paper] Pretreatment of anaerobic digester samples by hydrochloric acid for solution-state 1H and 13C NMR spectroscopic characterization of organic matter.
Pretreatment of anaerobic digester samples by hydrochloric acid for solution-state 1H and 13C NMR spectroscopic characterization of organic matter.
Pretreatment of anaerobic digester samples by hydrochloric acid for solution-state 1H and 13C NMR spectroscopic characterization of organic matter.
Chemosphere. 2018 Feb 05;199:201-209
Authors: Shakeri Yekta S, Hedenström M, Stehr JE, Dario M, Hertkorn N, Björn A
Abstract
Pretreatment of anaerobic digester samples by hydrochloric acid (HCl) resulted in removal of Fe-based...
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02-14-2018 04:47 PM
Alanine 501 Mutations in Penicillin-Binding Protein 2 from Neisseria gonorrhoeae: Structure, Mechanism, and Effectson Cephalosporin Resistance and Biological Fitness
Alanine 501 Mutations in Penicillin-Binding Protein 2 from Neisseria gonorrhoeae: Structure, Mechanism, and Effectson Cephalosporin Resistance and Biological Fitness
http://pubs.acs.org/appl/literatum/publisher/achs/journals/content/bichaw/0/bichaw.ahead-of-print/acs.biochem.6b01030/20170216/images/medium/bi-2016-01030j_0008.gif
Biochemistry
DOI: 10.1021/acs.biochem.6b01030
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02-17-2017 07:32 AM
Unravelling the secret of antibiotic resistance - Phys.Org
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Phys.Org
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Unravelling the secret of antibiotic resistance
Phys.Org
A recent £17 million investment in some of the best nuclear magnetic resonance and electron microscopy facilities in the world is now enabling scientists to remain at the forefront of research into complex proteins. The University of Leeds has played a ...
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Unravelling the secret of antibiotic resistance - Phys.Org
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03-25-2016 04:12 PM
NMR Structure and Calcium-Binding Properties of the Tellurite Resistance Protein TerD from Klebsiella pneumoniae.
NMR Structure and Calcium-Binding Properties of the Tellurite Resistance Protein TerD from Klebsiella pneumoniae.
NMR Structure and Calcium-Binding Properties of the Tellurite Resistance Protein TerD from Klebsiella pneumoniae.
J Mol Biol. 2010 Nov 25;
Authors: Pan YR, Lou YC, Seven AB, Rizo J, Chen C
The tellurium oxyanion, TeO(3)(2-), has been used in the treatment of infectious diseases caused by mycobacteria. However, many pathogenic bacteria show tellurite resistance. Several tellurite resistance genes have been identified, and these genes...
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11-30-2010 08:14 PM
[NMR paper] Flavonoid binding to a multi-drug-resistance transporter protein: an STD-NMR study.
Flavonoid binding to a multi-drug-resistance transporter protein: an STD-NMR study.
Related Articles Flavonoid binding to a multi-drug-resistance transporter protein: an STD-NMR study.
Anal Bioanal Chem. 2004 Aug;379(7-8):1045-9
Authors: Nissler L, Gebhardt R, Berger S
Flavonoids are well known to inhibit the function of the multi-drug-resistance (mdr) transporter by interacting with their ATP binding domains. The precise orientation of these molecules inside the ATP binding pocket is still unclear. We applied the saturation transfer...
A Specialized Polythioamide-Binding Protein Confers Antibiotic Self-Resistance in Anaerobic Bacteria
Linear Mode
