Solution NMR backbone assignments of disordered Olduvai protein domain CON1 employing Halpha-detected experiments
 

Solution NMR backbone assignments of disordered Olduvai protein domain CON1 employing Halpha-detected experiments

Olduvai protein domains, encoded by the NBPF gene family, are responsible for the largest increase in copy number of any protein-coding region in the human genome. This has spawned various genetics studies which have linked these domains to human brain development and divergence from our primate ancestors, as well as currently relevant cognitive diseases such as schizophrenia and autism spectrum disorder (ASD). There are six separate Olduvai domains which together form the majority of the...

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