Solid-State NMR of Membrane Proteins in Lipid Bilayers: To Spin or Not To Spin?
 

Solid-State NMR of Membrane Proteins in Lipid Bilayers: To Spin or Not To Spin?

ConspectusMembrane proteins mediate a plethora of cellular functions and represent important targets for drug development. Unlike soluble proteins, membrane proteins require native-like environments to fold correctly and be active. Therefore, modern structural biology techniques have aimed to determine the structure and dynamics of these membrane proteins at physiological temperature and in liquid crystalline lipid bilayers. With the flourishing of new NMR methodologies and improvements in...

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