Role of rotational motion in diffusion NMR experiments on supramolecular assemblies: application to Sup35NM fibrils
 

Role of rotational motion in diffusion NMR experiments on supramolecular assemblies: application to Sup35NM fibrils

Pulsed-field gradient (PFG) NMR is an important tool for characterization of biomolecules and supramolecular assemblies. However, for micron-sized objects, such as amyloid fibrils, these experiments become difficult to interpret because in addition to translational diffusion they are also sensitive to rotational diffusion. We have constructed a mathematical theory describing the outcome of PFG NMR experiments on rod-like fibrils. To test its validity, we have studied the fibrils formed by...

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