Protein complexes studied by NMR spectroscopy.
 

Protein complexes studied by NMR spectroscopy.

http://www.ncbi.nlm.nih.gov/corehtml...PubMedLink.gif Related Articles Protein complexes studied by NMR spectroscopy.

Curr Opin Biotechnol. 1996 Aug;7(4):403-8

Authors: Wand AJ, Englander SW

Recent advances in NMR methods now allow protein complexes to be studied in great detail in a wide range of solution conditions. Isotope-enrichment strategies, resonance-assignment approaches and structural-determination methods have evolved to the point where almost any type of complex involving proteins of reasonable size may be studied in a straightforward way. A variety of isotope editing and filtering strategies underlie these powerful methodologies. Approaches to the characterization of the dynamics of protein complexes have also matured to the point where detailed studies of the effects of complexation on dynamics can be studied over a wide range of timescales.

PMID: 8768898 [PubMed - indexed for MEDLINE]



Source: PubMed