BioNMR
NMR aggregator & online community since 2003
BioNMR    
Learn or help to learn NMR - get free NMR books!
 

Go Back   BioNMR > Educational resources > Journal club
Advanced Search



Jobs Groups Conferences Literature Pulse sequences Software forums Programs Sample preps Web resources BioNMR issues


Webservers
NMR processing:
MDD
NMR assignment:
Backbone:
Autoassign
MARS
UNIO Match
PINE
Side-chains:
UNIO ATNOS-Ascan
NOEs:
UNIO ATNOS-Candid
UNIO Candid
ASDP
Structure from NMR restraints:
Ab initio:
GeNMR
Cyana
XPLOR-NIH
ASDP
UNIO ATNOS-Candid
UNIO Candid
Fragment-based:
BMRB CS-Rosetta
Rosetta-NMR (Robetta)
Template-based:
GeNMR
I-TASSER
Refinement:
Amber
Structure from chemical shifts:
Fragment-based:
WeNMR CS-Rosetta
BMRB CS-Rosetta
Homology-based:
CS23D
Simshift
Torsion angles from chemical shifts:
Preditor
TALOS
Promega- Proline
Secondary structure from chemical shifts:
CSI (via RCI server)
TALOS
MICS caps, β-turns
d2D
PECAN
Flexibility from chemical shifts:
RCI
Interactions from chemical shifts:
HADDOCK
Chemical shifts re-referencing:
Shiftcor
UNIO Shiftinspector
LACS
CheckShift
RefDB
NMR model quality:
NOEs, other restraints:
PROSESS
PSVS
RPF scores
iCing
Chemical shifts:
PROSESS
CheShift2
Vasco
iCing
RDCs:
DC
Anisofit
Pseudocontact shifts:
Anisofit
Protein geomtery:
Resolution-by-Proxy
PROSESS
What-If
iCing
PSVS
MolProbity
SAVES2 or SAVES4
Vadar
Prosa
ProQ
MetaMQAPII
PSQS
Eval123D
STAN
Ramachandran Plot
Rampage
ERRAT
Verify_3D
Harmony
Quality Control Check
NMR spectrum prediction:
FANDAS
MestReS
V-NMR
Flexibility from structure:
Backbone S2
Methyl S2
B-factor
Molecular dynamics:
Gromacs
Amber
Antechamber
Chemical shifts prediction:
From structure:
Shiftx2
Sparta+
Camshift
CH3shift- Methyl
ArShift- Aromatic
ShiftS
Proshift
PPM
CheShift-2- Cα
From sequence:
Shifty
Camcoil
Poulsen_rc_CS
Disordered proteins:
MAXOCC
Format conversion & validation:
CCPN
From NMR-STAR 3.1
Validate NMR-STAR 3.1
NMR sample preparation:
Protein disorder:
DisMeta
Protein solubility:
camLILA
ccSOL
Camfold
camGroEL
Zyggregator
Isotope labeling:
UPLABEL
Solid-state NMR:
sedNMR


Reply
Thread Tools Search this Thread Rate Thread Display Modes
  #1  
Unread 08-21-2010, 11:45 PM
nmrlearner's Avatar
Senior Member
 
Join Date: Jan 2005
Posts: 17,565
Points: 193,617, Level: 100
Points: 193,617, Level: 100 Points: 193,617, Level: 100 Points: 193,617, Level: 100
Level up: 0%, 0 Points needed
Level up: 0% Level up: 0% Level up: 0%
Activity: 50.7%
Activity: 50.7% Activity: 50.7% Activity: 50.7%
Last Achievements
Award-Showcase
NMR Credits: 0
NMR Points: 193,617
Downloads: 0
Uploads: 0
Default Progress in multidimensional NMR investigations of peptide and protein 3-D structures

Progress in multidimensional NMR investigations of peptide and protein 3-D structures in solution. From structure to functional aspects.

Related Articles Progress in multidimensional NMR investigations of peptide and protein 3-D structures in solution. From structure to functional aspects.

Biochimie. 1992 Sep-Oct;74(9-10):825-36

Authors: Bonmatin JM, Genest M, Petit MC, Gincel E, Simorre JP, Cornet B, Gallet X, Caille A, Labbé H, Vovelle F

2-D and 3-D NMR techniques were used to investigate the conformations in solution of several peptides and proteins for which crystalline structures are not available yet. Insect defensin A is a small (40 aa) antibiotic protein exhibiting a characteristic 'loop-helix-beta-sheet' structure. A striking analogy was found with charybdotoxin, a scorpion toxin in which a CSH (cysteine stabilized alpha-helix) motif is also present. Wheat phospholipid transfer protein (PLTP) (90 aa) has a 3-D structure resulting from the packing of four helices and of a C-terminal less well-defined fragment. Preliminary results show that PLTP forms a complex with lyso-PC and that such an interaction results in a conformational change affecting principally the C-terminal half of the protein. A last example is given with surfactin, a lipopeptide biosurfactant from bacterial origin. Its protonated form shows a very compact structure in which the two acidic residues located on the top of a 'horse saddle' topology face each other, whereas the ionized form could adopt a more extended conformation. A common property of these compounds is their capacity to interact with lipids. The present structural data open the way for a further establishment of structure-activity relationships.

PMID: 1467342 [PubMed - indexed for MEDLINE]



Source: PubMed
Reply With Quote


Did you find this post helpful? Yes | No

Reply
Similar Threads
Thread Thread Starter Forum Replies Last Post
Revealing Protein Structures in Solid-Phase Peptide Synthesis by 13C Solid-State NMR: Evidence of Excessive Misfolding for Alzheimer’s ?
Revealing Protein Structures in Solid-Phase Peptide Synthesis by 13C Solid-State NMR: Evidence of Excessive Misfolding for Alzheimer’s ? Songlin Wang and Yoshitaka Ishii http://pubs.acs.org/appl/literatum/publisher/achs/journals/content/jacsat/0/jacsat.ahead-of-print/ja212190z/aop/images/medium/ja-2011-12190z_0002.gif Journal of the American Chemical Society DOI: 10.1021/ja212190z http://feeds.feedburner.com/~ff/acs/jacsat?d=yIl2AUoC8zA http://feeds.feedburner.com/~r/acs/jacsat/~4/6EE7uthrnLg
nmrlearner Journal club 0 01-31-2012 08:34 PM
[NMR paper] The fumarate sensor DcuS: progress in rapid protein fold elucidation by combining pro
The fumarate sensor DcuS: progress in rapid protein fold elucidation by combining protein structure prediction methods with NMR spectroscopy. Related Articles The fumarate sensor DcuS: progress in rapid protein fold elucidation by combining protein structure prediction methods with NMR spectroscopy. J Magn Reson. 2005 Apr;173(2):310-6 Authors: Meiler J, Baker D We illustrate how moderate resolution protein structures can be rapidly obtained by interlinking computational prediction methodologies with un- or partially assigned NMR data. To...
nmrlearner Journal club 0 11-25-2010 08:21 PM
[NMR paper] Structural investigations of a human calcitonin-derived carrier peptide in a membrane
Structural investigations of a human calcitonin-derived carrier peptide in a membrane environment by solid-state NMR. Related Articles Structural investigations of a human calcitonin-derived carrier peptide in a membrane environment by solid-state NMR. Biochemistry. 2004 Oct 5;43(39):12459-68 Authors: Wagner K, Beck-Sickinger AG, Huster D Previous studies have shown that human calcitonin (hCT) and its C-terminal fragment hCT(9-32) translocate in nasal epithelium. Moreover, hCT(9-32) was used as a carrier to internalize efficiently the green...
nmrlearner Journal club 0 11-24-2010 10:01 PM
[NMR tweet] [ebook] Progress in Nuclear Magnetic Spectroscopy Volume 1 Issue 1: Progress in Nucle
Progress in Nuclear Magnetic Spectroscopy Volume 1 Issue 1: Progress in Nuclear Magnetic Resonance Spect... http://bit.ly/do1tRf Published by ebook30 (EBOOK30.com) on 2010-11-22T04:38:13Z Source: Twitter
nmrlearner Twitter NMR 0 11-22-2010 05:39 AM
[NMR tweet] [science] Progress in Nuclear Magnetic Spectroscopy Volume 1 Issue 1: Progress in Nuc
Progress in Nuclear Magnetic Spectroscopy Volume 1 Issue 1: Progress in Nuclear Magnetic Resonance Spe... http://bit.ly/do1tRf Published by ebook30 (EBOOK30.com) on 2010-11-22T04:29:55Z Source: Twitter
nmrlearner Twitter NMR 0 11-22-2010 04:33 AM
[NMR paper] Solution structures of staphylococcal nuclease from multidimensional, multinuclear NM
Solution structures of staphylococcal nuclease from multidimensional, multinuclear NMR: nuclease-H124L and its ternary complex with Ca2+ and thymidine-3',5'-bisphosphate. Related Articles Solution structures of staphylococcal nuclease from multidimensional, multinuclear NMR: nuclease-H124L and its ternary complex with Ca2+ and thymidine-3',5'-bisphosphate. J Biomol NMR. 1997 Sep;10(2):143-64 Authors: Wang J, Truckses DM, Abildgaard F, Dzakula Z, Zolnai Z, Markley JL The solution structures of staphylococcal nuclease (nuclease) H124L and its...
nmrlearner Journal club 0 08-22-2010 05:08 PM
[NMR paper] NMR structures of a mitochondrial transit peptide from the green alga Chlamydomonas r
NMR structures of a mitochondrial transit peptide from the green alga Chlamydomonas reinhardtii. http://www.ncbi.nlm.nih.gov/corehtml/query/egifs/http:--linkinghub.elsevier.com-ihub-images-PubMedLink.gif Related Articles NMR structures of a mitochondrial transit peptide from the green alga Chlamydomonas reinhardtii. FEBS Lett. 1996 Aug 5;391(1-2):203-8 Authors: Lancelin JM, Gans P, Bouchayer E, Bally I, Arlaud GJ, Jacquot JP The 26-amino-acid pre-sequence of the ATP synthase beta subunit that directs the protein from the cytosol to...
nmrlearner Journal club 0 08-22-2010 02:20 PM
[NMR paper] Trans-membrane peptide and protein structures in fluid membranes via NMR.
Trans-membrane peptide and protein structures in fluid membranes via NMR. http://www.ncbi.nlm.nih.gov/corehtml/query/egifs/http:--www.pubmedcentral.nih.gov-corehtml-pmc-pmcgifs-pubmed-pmc.gif Related Articles Trans-membrane peptide and protein structures in fluid membranes via NMR. Biophys J. 1995 Nov;69(5):1631-2 Authors: Bloom M
nmrlearner Journal club 0 08-22-2010 03:50 AM


Thread Tools Search this Thread
Search this Thread:

Advanced Search
Display Modes Rate This Thread
Rate This Thread:

Posting Rules
You may not post new threads
You may not post replies
You may not post attachments
You may not edit your posts

BB code is On
Smilies are On
[IMG] code is On
HTML code is On
Trackbacks are Off
Pingbacks are Off
Refbacks are Off



BioNMR advertisements to pay for website hosting and domain registration. Nobody does it for us.



Powered by vBulletin® Version 3.7.3
Copyright ©2000 - 2017, Jelsoft Enterprises Ltd.
Copyright, BioNMR.com, 2003-2013
Search Engine Friendly URLs by vBSEO 3.6.0

All times are GMT. The time now is 03:14 PM.


Map