Partial alignment of biomolecules: an aid to NMR characterization.
 

Partial alignment of biomolecules: an aid to NMR characterization.

Related Articles Partial alignment of biomolecules: an aid to NMR characterization.

Curr Opin Chem Biol. 2001 Oct;5(5):584-90

Authors: Prestegard JH, Kishore AI

Partial alignment of biomolecules in solution has added a new dimension to structural investigation by high-resolution NMR methods. Applications to proteins, nucleic acids and carbohydrates now abound. Limitations initially associated with compatibility of biomolecules with the liquid-crystal media commonly used to achieve alignment have begun to disappear. This is, in part, a result of the introduction of a wide variety of new media. Future applications to biologically important problems such as the structural organization of multi-domain proteins and multi-protein assemblies look very promising.

PMID: 11578934 [PubMed - indexed for MEDLINE]



Source: PubMed