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Food Funct. 2015 Apr;6(4):1090-7
Authors: Moazzami AA, Frank S, Gombert A, Sus N, Bayram B, Rimbach G, Frank J
Abstract
The essential function of vitamin E in vivo is not fully understood. Several studies addressed changes in the pattern of gene expression induced by vitamin E, but often did not investigate if these changes altered biochemical pathways and are eventually translated into biological function. We therefore used (1)H-NMR metabolomics to investigate the biochemical effects in the liver of rats caused by long-term feeding with diets deficient (dVE; ?-tocopherol (?T),
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Non-targeted 1H-NMR-metabolomics suggest the induction of master regulators of energy metabolism in the liver of vitamin E-deficient rats.
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