NMR studies of the sporulation protein SpoIIAA: implications for the regulation of th
 

NMR studies of the sporulation protein SpoIIAA: implications for the regulation of the transcription factor sigmaF in Bacillus subtilis.

Related Articles NMR studies of the sporulation protein SpoIIAA: implications for the regulation of the transcription factor sigmaF in Bacillus subtilis.

J Biomol NMR. 2001 Apr;19(4):293-304

Authors: Kovacs H, Comfort D, Lord M, Yudkin M, Campbell ID, Nilges M

SpoIIAA participates in a four-component mechanism for phosphorylation-dependent transcription control at the outset of sporulation. We report the refinement of the solution structure of SpoIIAA by using the automated iterative NOE assignment method ARIA. To complement the structural data, the protein dynamics were determined by measuring the T1, T2 and NOE of the backbone 15N-nuclei. The refined structure permits a discussion of the structural features that are important for the function of SpoIIAA in the regulation of the sporulation sigma factor sigmaF, and for homologous regulatory pathways present in B. subtilis and in other bacilli.

PMID: 11370776 [PubMed - indexed for MEDLINE]



Source: PubMed