NMR studies on the solution structure of a deletion mutant of the transcarboxylase bi
 

NMR studies on the solution structure of a deletion mutant of the transcarboxylase biotin carrier subunit.

Related Articles NMR studies on the solution structure of a deletion mutant of the transcarboxylase biotin carrier subunit.

Int J Biol Macromol. 2002 Oct 1;30(5):233-42

Authors: Jank MM, Sadowsky JD, Peikert C, Berger S

A deletion mutant of the transcarboxylase biotin carrier protein was completely labeled with 13C and 15N. A multitude of 2D and 3D NMR spectra were recorded and assigned. An NMR solution structure was derived from the data and compared in detail with the recently published structure of the wild-type. It is shown that deletion of 30% of the amino acids does not alter the structure of the rigid protein core.

PMID: 12297230 [PubMed - indexed for MEDLINE]



Source: PubMed